Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Peptide Science"
DOI: 10.1002/pep2.24209
Abstract: Melanocortin receptors are pharmaceutically important receptors that are involved in complex physiological functions. They have been associated with various diseases including obesity, erectile dysfunction, acne, and skin cancer. It has been challenging to transform nonselective… read more here.
Keywords: skin; towards melanocortin; frog skin; selectivity towards ... See more keywords
Comparative Analysis of Anuran Amphibian Skin Microbiomes Across Inland and Coastal Wetlands
Sign Up to like & getrecommendations! Published in 2018 at "Microbial Ecology"
DOI: 10.1007/s00248-018-1295-9
Abstract: Amphibians host a community of microbes on their skin that helps resist infectious disease via the dual influence of anti-pathogenic microbial species and emergent community dynamics. Many frogs rely on freshwater habitats, but salinization is… read more here.
Keywords: comparative analysis; skin; inland coastal; frog skin ... See more keywords
Effect of magnetic fields on green color formation in frog skin
Sign Up to like & getrecommendations! Published in 2017 at "AIP Advances"
DOI: 10.1063/1.4976958
Abstract: The present work is focused on a dynamic and efficient optical control system that is made possible by investigation of the body surfaces of various animals. Specifically, we expect Japanese tree frog (Hyla japonica) skin… read more here.
Keywords: color; frog skin; color formation;
Sigma-1 Receptor Antagonists Haloperidol and Chlorpromazine Modulate the Effect of Glutoxim on Na+ Transport in Frog Skin
Sign Up to like & getrecommendations! Published in 2019 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672919010186
Abstract: Using voltage-clamp technique, the involvement of sigma-1 receptors in the regulation of Na+ transport in frog skin by the immunomodulatory drug glutoxim was investigated. We have shown for the first time that preincubation of the… read more here.
Keywords: transport frog; glutoxim; transport; frog skin ... See more keywords
The frog skin that saved fifty million lives — from the bench-side to world-wide
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology and Hepatology From Bed to Bench"
DOI: 10.22037/ghfbb.v0i0.1597
Abstract: ( Please cite as: Sachar D, Hirschhorn N. The frog skin that saved fifty million lives — from the bench-side to world-wide. Gastroenterol Hepatol Bed Bench 2019;12(1):1-2). read more here.
Keywords: fifty million; lives bench; million lives; skin saved ... See more keywords
Analogs of the Frog-skin Antimicrobial Peptide Temporin 1Tb Exhibit a Wider Spectrum of Activity and a Stronger Antibiofilm Potential as Compared to the Parental Peptide
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2017.00024
Abstract: The frog skin-derived peptide Temporin 1Tb (TB) has gained increasing attention as novel antimicrobial agent for the treatment of antibiotic-resistant and/or biofilm-mediated infections. Nevertheless, such a peptide possesses a preferential spectrum of action against Gram-positive… read more here.
Keywords: peptide; parental peptide; frog skin; peptide temporin ... See more keywords
Frog Skin Innate Immune Defences: Sensing and Surviving Pathogens
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.03128
Abstract: Amphibian skin is a mucosal surface in direct and continuous contact with a microbially diverse and laden aquatic and/or terrestrial environment. As such, frog skin is an important innate immune organ and first line of… read more here.
Keywords: innate; innate immune; skin innate; frog skin ... See more keywords