Frontline treatment patterns and outcomes among older adults with acute myeloid leukemia: A population-based analysis in the modern era.
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DOI: 10.1002/cncr.33873
Abstract: BACKGROUND Traditionally, conventional induction chemotherapy has been the primary frontline treatment for acute myeloid leukemia (AML); however, older adults are often poor chemotherapy candidates. Recently, several nonconventional frontline AML regimens, including hypomethylating agents, the BCL-2… read more here.
Keywords: frontline treatment; treatment; older adults; population based ... See more keywords
Frontline treatment of diffuse large B‐cell lymphoma: Beyond R‐CHOP
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DOI: 10.1002/hon.2613
Abstract: Although the majority of patients with diffuse large B‐cell lymphoma (DLBCL) can be cured with the standard immunochemotherapy R‐CHOP, one‐third of them relapses with a dismal outcome in most cases. In the recent years, remarkable… read more here.
Keywords: cell; chop; frontline treatment; large cell ... See more keywords
Maintenance rituximab or observation after frontline treatment with bendamustine‐rituximab for follicular lymphoma
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DOI: 10.1111/bjh.15720
Abstract: Bendamustine (B) with rituximab (R) is a standard frontline treatment for medically fit follicular lymphoma (FL) patients. The safety and efficacy of maintenance rituximab (MR) after BR induction has not been formally compared to observation… read more here.
Keywords: rituximab; maintenance rituximab; maintenance; follicular lymphoma ... See more keywords
The interval between frontline treatment and the second relapse (PFS2) predicts survival from the second relapse in follicular lymphoma patients
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DOI: 10.1111/ejh.13556
Abstract: Follicular lymphoma (FL) is the most frequent indolent B-cell lymphoma. The introduction of immunotherapy has greatly improved outcomes for FL patients, with a median overall survival (OS) now approaching 20 years. However, relapses are continuously… read more here.
Keywords: follicular lymphoma; relapse; frontline treatment; second relapse ... See more keywords
Advances and Personalized Approaches in the Frontline Treatment of T-Cell Lymphomas
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DOI: 10.3390/jpm12020267
Abstract: Peripheral T-cell lymphomas (PTCLs) are a rare and heterogenous subset of non-Hodgkin lymphoma characterized by an aggressive clinical course. Historically, the treatment of PTCLs have been analogous to that of aggressive B-cell lymphomas; however, it… read more here.
Keywords: personalized approaches; frontline treatment; cell lymphomas; advances personalized ... See more keywords