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Published in 2018 at "Brain Imaging and Behavior"
DOI: 10.1007/s11682-018-9852-x
Abstract: To evaluate whether occupational attainment influences the trajectory of longitudinal cognitive decline in behavioral variant frontotemporal degeneration (bvFTD). Single-center, retrospective, longitudinal study. Sixty-three patients meeting consensus criteria for bvFTD underwent evaluation at the University of…
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Keywords:
decline;
longitudinal decline;
frontotemporal degeneration;
occupational attainment ... See more keywords
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Published in 2022 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.12.005
Abstract: To understand how glia may be altered in frontotemporal degeneration with tau pathology (FTD-tau), we used a NanoString glial profiling panel to measure 770 transcripts related to glial biology in human control (n = 8), Alzheimer's disease…
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Keywords:
glial profiling;
ftd tau;
frontotemporal degeneration;
profiling human ... See more keywords
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Published in 2024 at "Neurology"
DOI: 10.1212/wnl.0000000000207926
Abstract: BACKGROUND AND OBJECTIVES Clinical trials developing therapeutics for frontotemporal degeneration (FTD) focus on pathogenic variant carriers at preclinical stages. Objective, quantitative clinical assessment tools are needed to track stability and delayed disease onset. Natural speech…
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Keywords:
speech;
natural speech;
frontotemporal degeneration;
pathogenic variants ... See more keywords
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Published in 2024 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2024.1374827
Abstract: In addition to Alzheimer’s disease (AD), the hippocampus is now known to be affected in variants of frontotemporal degeneration (FTD). In semantic variant primary progressive aphasia (svPPA), characterized by language impairments, hippocampal atrophy is greater…
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Keywords:
memory;
visual memory;
hippocampal atrophy;
frontotemporal degeneration ... See more keywords