Articles with "frontotemporal degeneration" as a keyword



Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration

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Published in 2018 at "Brain Imaging and Behavior"

DOI: 10.1007/s11682-018-9852-x

Abstract: To evaluate whether occupational attainment influences the trajectory of longitudinal cognitive decline in behavioral variant frontotemporal degeneration (bvFTD). Single-center, retrospective, longitudinal study. Sixty-three patients meeting consensus criteria for bvFTD underwent evaluation at the University of… read more here.

Keywords: decline; longitudinal decline; frontotemporal degeneration; occupational attainment ... See more keywords

Glial profiling of human tauopathy brain demonstrates enrichment of astrocytic transcripts in tau-related frontotemporal degeneration

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Published in 2022 at "Neurobiology of Aging"

DOI: 10.1016/j.neurobiolaging.2021.12.005

Abstract: To understand how glia may be altered in frontotemporal degeneration with tau pathology (FTD-tau), we used a NanoString glial profiling panel to measure 770 transcripts related to glial biology in human control (n = 8), Alzheimer's disease… read more here.

Keywords: glial profiling; ftd tau; frontotemporal degeneration; profiling human ... See more keywords

Changes in Digital Speech Measures in Asymptomatic Carriers of Pathogenic Variants Associated With Frontotemporal Degeneration.

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Published in 2024 at "Neurology"

DOI: 10.1212/wnl.0000000000207926

Abstract: BACKGROUND AND OBJECTIVES Clinical trials developing therapeutics for frontotemporal degeneration (FTD) focus on pathogenic variant carriers at preclinical stages. Objective, quantitative clinical assessment tools are needed to track stability and delayed disease onset. Natural speech… read more here.

Keywords: speech; natural speech; frontotemporal degeneration; pathogenic variants ... See more keywords

Hemispheric asymmetries in hippocampal volume related to memory in left and right temporal variants of frontotemporal degeneration

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Published in 2024 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2024.1374827

Abstract: In addition to Alzheimer’s disease (AD), the hippocampus is now known to be affected in variants of frontotemporal degeneration (FTD). In semantic variant primary progressive aphasia (svPPA), characterized by language impairments, hippocampal atrophy is greater… read more here.

Keywords: memory; visual memory; hippocampal atrophy; frontotemporal degeneration ... See more keywords