Apathy and Functional Impairment in the Course of Behavioral Variant Frontotemporal Dementia
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DOI: 10.1001/jamanetworkopen.2022.45656
Abstract: This cohort study analyzes patterns of apathy and functional impairment in patients with progressive severity of behavioral variant frontotemporal dementia. read more here.
Keywords: apathy functional; functional impairment; variant frontotemporal; frontotemporal dementia ... See more keywords
Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.
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DOI: 10.1001/jamaneurol.2019.4284
Abstract: Importance Individuals with tuberous sclerosis complex can develop a progressive neuropsychiatric syndrome known as tuberous sclerosis-associated neuropsychiatric disorders. Tuberous sclerosis-associated neuropsychiatric disorders symptoms overlap with clinical criteria for frontotemporal dementia, yet the association between the… read more here.
Keywords: sclerosis; tuberous sclerosis; frontotemporal dementia; sclerosis associated ... See more keywords
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2023.0001
Abstract: This case-control study assesses the anatomical and physiological underpinnings of visual artistic creativity in individuals with frontotemporal dementia. read more here.
Keywords: prevalence timing; network localization; creativity; timing network ... See more keywords
Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2022.2075
Abstract: Key Points Question Do psychosis and dementia share brain-behavioral alterations? Findings In this diagnostic/prognostic study including 1870 patients, patients with schizophrenia expressed the neuroanatomical pattern of behavioral-variant frontotemporal dementia more strongly (41%) than that of… read more here.
Keywords: dementia using; psychosis frontotemporal; exploring links; dementia ... See more keywords
Neural correlates of fat preference in frontotemporal dementia: translating insights from the obesity literature
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DOI: 10.1002/acn3.51369
Abstract: Alterations in eating behaviour are one of the diagnostic features of behavioural variant frontotemporal dementia (bvFTD). It is hypothesised that underlying brain network disturbances and atrophy to key structures may affect macronutrient preference in bvFTD.… read more here.
Keywords: frontotemporal dementia; preference; fat preference; neural correlates ... See more keywords
The CBI‐R detects early behavioural impairment in genetic frontotemporal dementia
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DOI: 10.1002/acn3.51544
Abstract: Behavioural dysfunction is a key feature of genetic frontotemporal dementia (FTD) but validated clinical scales measuring behaviour are lacking at present. read more here.
Keywords: early behavioural; detects early; frontotemporal dementia; genetic frontotemporal ... See more keywords
Modifiable potential risk factors in familial and sporadic frontotemporal dementia
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DOI: 10.1002/acn3.51619
Abstract: Only a few studies have evaluated modifiable risk factors for frontotemporal dementia (FTD). Here, we evaluated several modifiable factors and their association with disease phenotype, genotype, and prognosis in a large study population including Finnish… read more here.
Keywords: frontotemporal dementia; risk factors; potential risk; modifiable potential ... See more keywords
CYLD variants identified in Alzheimer's disease and frontotemporal dementia patients
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DOI: 10.1002/acn3.51655
Abstract: CYLD was a novel causative gene for frontotemporal dementia (FTD) and amyotrophic lateral sclerosis. Given the clinical and pathological overlap of FTD and Alzheimer's disease (AD), it is necessary to screen CYLD in AD patients… read more here.
Keywords: variants identified; frontotemporal dementia; alzheimer disease; cyld variants ... See more keywords
CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia
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DOI: 10.1002/acn3.51672
Abstract: Neuroinflammation has been shown to be an important pathophysiological disease mechanism in frontotemporal dementia (FTD). This includes activation of microglia, a process that can be measured in life through assaying different glia‐derived biomarkers in cerebrospinal… read more here.
Keywords: elevated subset; markers elevated; glial markers; dementia ... See more keywords
C9orf72 expansions are the most common cause of genetic frontotemporal dementia in a Southeast Asian cohort
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DOI: 10.1002/acn3.51744
Abstract: Frontotemporal dementia (FTD) encompasses a spectrum of neurodegenerative disorders, including behavioural variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non‐fluent variant PPA (nfvPPA). While a strong genetic component is implicated in FTD, genetic… read more here.
Keywords: southeast asian; frontotemporal dementia; c9orf72 expansions; ftd ... See more keywords
Eating peptides: biomarkers of neurodegeneration in amyotrophic lateral sclerosis and frontotemporal dementia
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DOI: 10.1002/acn3.721
Abstract: Physiological changes potentially influence disease progression and survival along the Amyotrophic Lateral Sclerosis (ALS)‐Frontotemporal dementia (FTD) spectrum. The peripheral peptides that regulate eating and metabolism may provide diagnostic, metabolic, and progression biomarkers. The current study… read more here.
Keywords: amyotrophic lateral; frontotemporal dementia; eating peptides; lateral sclerosis ... See more keywords