In vitro testing of flash-frozen sublingual membranes for storage and reproducible permeability studies of macromolecular drugs from solution or nanofiber mats.
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DOI: 10.1016/j.ijpharm.2019.118711
Abstract: Sublingual drug delivery allows systemic delivery of drug without difficulties connected with the gastrointestinal pathway. We developed a new simple protocol for easy-to-use processing and storage of porcine sublingual mucosal membrane for in vitro studies… read more here.
Keywords: storage; sublingual membranes; frozen sublingual; permeability ... See more keywords