Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras
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DOI: 10.1038/s41467-017-01019-z
Abstract: Yeast and cancer cells share the unusual characteristic of favoring fermentation of sugar over respiration. We now reveal an evolutionary conserved mechanism linking fermentation to activation of Ras, a major regulator of cell proliferation in… read more here.
Keywords: fructose bisphosphate; fru1 6bisp; activation ras; yeast ... See more keywords
Aberrant Intracellular pH Regulation Limiting Glyceraldehyde-3-Phosphate Dehydrogenase Activity in the Glucose-Sensitive Yeast tps1Δ Mutant
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DOI: 10.1128/mbio.02199-20
Abstract: Glucose catabolism is the backbone of metabolism in most organisms. In spite of numerous studies and extensive knowledge, major controls on glycolysis and its connections to the other metabolic pathways remain to be discovered. A… read more here.
Keywords: tps1 mutant; hyperaccumulation; tps1 cells; tps1 ... See more keywords