Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs).
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DOI: 10.1016/j.thromres.2017.11.012
Abstract: The circulating zymogen form of Factor VII activating protease (FSAP) can be activated by histones and nucleosomes in vivo. These cell-death-associated nuclear factors are also actively extruded into the extracellular space by neutrophils through a… read more here.
Keywords: protease fsap; activating protease; factor vii; neutrophil extracellular ... See more keywords
FSAP Protects against Histone-Mediated Increase in Endothelial Permeability In Vitro
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DOI: 10.3390/ijms232213706
Abstract: Factor-VII-activating protease (FSAP) is involved in the regulation of hemostasis and inflammation. Extracellular histones play a role in inflammation and the conversion of latent pro-FSAP into active FSAP. FSAP has been shown to regulate endothelial… read more here.
Keywords: histone mediated; fsap; endothelial permeability; spd fsap ... See more keywords
Factor VII Activating Protease (FSAP) and Its Importance in Hemostasis—Part I: FSAP Structure, Synthesis and Activity Regulation: A Narrative Review
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DOI: 10.3390/ijms24065473
Abstract: Factor VII activating protease (FSAP) was first isolated from human plasma less than 30 years ago. Since then, many research groups have described the biological properties of this protease and its role in hemostasis and… read more here.
Keywords: structure; factor vii; fsap; hemostasis ... See more keywords