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   Articles with "fsgs" as a keyword



Removal of focal segmental glomerulosclerosis (FSGS) factor suPAR using CytoSorb

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recommendations! Published in 2017 at "Journal of Clinical Apheresis"

DOI: 10.1002/jca.21538

Abstract: Treatment of primary focal segmental glomerulosclerosis (FSGS) and its recurrence after kidney transplantation associated with rapid deterioration of kidney function remains to be challenging despite advances in immunosuppressive therapy. The presence of circulating factors has… read more here.

Keywords: focal segmental; glomerulosclerosis fsgs; using cytosorb; supar ... See more keywords

Dominant PAX2 mutations may cause steroid-resistant nephrotic syndrome and FSGS in children

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recommendations! Published in 2019 at "Pediatric Nephrology"

DOI: 10.1007/s00467-019-04256-0

Abstract: BackgroundHeterozygous PAX2 mutations cause renal coloboma syndrome (RCS) [OMIM no. 120330]. RCS is a renal syndromic disease encompassing retinal coloboma and sensorineural hearing loss. Recently, a causative role for PAX2 was reported in adult-onset nephrotic… read more here.

Keywords: resistant nephrotic; steroid resistant; pax2 mutations; fsgs ... See more keywords

Recent advances of animal model of focal segmental glomerulosclerosis

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recommendations! Published in 2018 at "Clinical and Experimental Nephrology"

DOI: 10.1007/s10157-018-1552-8

Abstract: In the last decade, great advances have been made in understanding the genetic basis for focal segmental glomerulosclerosis (FSGS). Animal models using specific gene disruption of the slit diaphragm and cytoskeleton of the foot process… read more here.

Keywords: focal segmental; segmental glomerulosclerosis; animal; fsgs ... See more keywords

Spontaneous remission of genetic, apparent primary, FSGS presenting with nephrotic syndrome challenges traditional notions of primary FSGS

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recommendations! Published in 2020 at "Journal of Nephrology"

DOI: 10.1007/s40620-020-00837-7

Abstract: A 26-year-old Caucasian female was referred for new onset nephrotic syndrome (NS). She was well until early June 2018 when she developed bilateral leg swelling followed by swelling of her arms and face. About 2… read more here.

Keywords: nephrology; primary fsgs; supplementary reference; fsgs ... See more keywords

Increasing Options for First-Line Therapy in Primary FSGS?

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recommendations! Published in 2019 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2018.10.016

Abstract: F ocal segmental glomerulosclerosis (FSGS) is a common pathologic diagnosis on kidney biopsy. It denotes focal and segmental intracapillary hyaline deposition and/or focal adhesions of capillaries to Bowman’s capsule. When it occurs without underlying alternate… read more here.

Keywords: options first; therapy; first line; increasing options ... See more keywords

P113 High levels of angiotensin receptor type 1 antibodies in a child with FSGS who had a renal transplant

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recommendations! Published in 2017 at "Human Immunology"

DOI: 10.1016/j.humimm.2017.06.173

Abstract: Focal Segmental Glomerulosclerosis (FSGS) can lead to ESRD requiring a renal transplant and the rate of recurrent FSGR (rFSGS) is high. The exact mechanisms of the pathogenesis of FSGS and rFSGS is unclear and both… read more here.

Keywords: transplant; angiotensin receptor; receptor type; renal transplant ... See more keywords

Management and long-term outcome of recurrent idiopathic FSGS in pediatric kidney transplant recipients

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-74184-z

Abstract: Focal segmental glomerulosclerosis (FSGS) is a major cause of pediatric kidney failure. Most cases of FSGS in children are idiopathic and have a high risk of post-transplantation recurrence and graft loss. Common treatments for recurrent… read more here.

Keywords: transplant recipients; idiopathic fsgs; pediatric kidney; fsgs ... See more keywords

P1808INHIBITION OF MIR-155 IMPROVES PROGNOSIS IN AN EXPERIMENTAL FSGS MOUSE MODEL BY REGULATING AUTOPHAGY

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recommendations! Published in 2020 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p1808

Abstract: Focal segmental glomerulosclerosis (FSGS), a podocytopathy, is one of the most common primary glomerular diseases causing end-stage renal disease in children. Its mechanisms remain unclear and the effective treatment lacks. MiR-155 is a typical multifunctional… read more here.

Keywords: p1808inhibition mir; mir 155; 155 improves; model ... See more keywords

#2862 Genetics and electron microscopy: complementary tools for management of focal segmental glomerulosclerosis?

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.436

Abstract: Focal segmental glomerular sclerosis (FSGS) defines a histologic lesion that represents a pattern of injury associated to different pathologic conditions affecting both children and adults. It is classified into primary forms, presumably immune-mediated, secondary forms,… read more here.

Keywords: genetics; therapy; response; secondary forms ... See more keywords

#296 A mid-study update on the ACTION3 pivotal Phase 3 trial assessing DMX-200 in patients with focal segmental glomerulosclerosis (FSGS)

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recommendations! Published in 2025 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaf116.0253

Abstract: Focal segmental glomerulosclerosis (FSGS) is a major cause of glomerular disease that can rapidly progress to end-stage kidney disease. Lack of safe and effective treatment represents a significant unmet need for patients with FSGS. Development… read more here.

Keywords: disease; action3; dmx 200; fsgs ... See more keywords

#1933 Clinico-pathologic classification of focal segmental glomerulosclerosis to inform on treatment and prognosis

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recommendations! Published in 2025 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaf116.1166

Abstract: Focal segmental glomerulosclerosis (FSGS) is classified into primary (idiopathic, immune-mediated), secondary (maladaptive, medication-induced or viral-associated), and genetic forms, each differing in disease progression and treatment responses. Despite advancements, misclassification of subtypes remains common due to… read more here.

Keywords: presumed primary; treatment; group; fsgs ... See more keywords