Removal of focal segmental glomerulosclerosis (FSGS) factor suPAR using CytoSorb
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DOI: 10.1002/jca.21538
Abstract: Treatment of primary focal segmental glomerulosclerosis (FSGS) and its recurrence after kidney transplantation associated with rapid deterioration of kidney function remains to be challenging despite advances in immunosuppressive therapy. The presence of circulating factors has… read more here.
Keywords: focal segmental; glomerulosclerosis fsgs; using cytosorb; supar ... See more keywords
Dominant PAX2 mutations may cause steroid-resistant nephrotic syndrome and FSGS in children
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DOI: 10.1007/s00467-019-04256-0
Abstract: BackgroundHeterozygous PAX2 mutations cause renal coloboma syndrome (RCS) [OMIM no. 120330]. RCS is a renal syndromic disease encompassing retinal coloboma and sensorineural hearing loss. Recently, a causative role for PAX2 was reported in adult-onset nephrotic… read more here.
Keywords: resistant nephrotic; steroid resistant; pax2 mutations; fsgs ... See more keywords
Recent advances of animal model of focal segmental glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-1552-8
Abstract: In the last decade, great advances have been made in understanding the genetic basis for focal segmental glomerulosclerosis (FSGS). Animal models using specific gene disruption of the slit diaphragm and cytoskeleton of the foot process… read more here.
Keywords: focal segmental; segmental glomerulosclerosis; animal; fsgs ... See more keywords
Spontaneous remission of genetic, apparent primary, FSGS presenting with nephrotic syndrome challenges traditional notions of primary FSGS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nephrology"
DOI: 10.1007/s40620-020-00837-7
Abstract: A 26-year-old Caucasian female was referred for new onset nephrotic syndrome (NS). She was well until early June 2018 when she developed bilateral leg swelling followed by swelling of her arms and face. About 2… read more here.
Keywords: nephrology; primary fsgs; supplementary reference; fsgs ... See more keywords
Increasing Options for First-Line Therapy in Primary FSGS?
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DOI: 10.1016/j.ekir.2018.10.016
Abstract: F ocal segmental glomerulosclerosis (FSGS) is a common pathologic diagnosis on kidney biopsy. It denotes focal and segmental intracapillary hyaline deposition and/or focal adhesions of capillaries to Bowman’s capsule. When it occurs without underlying alternate… read more here.
Keywords: options first; therapy; first line; increasing options ... See more keywords
P113 High levels of angiotensin receptor type 1 antibodies in a child with FSGS who had a renal transplant
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.173
Abstract: Focal Segmental Glomerulosclerosis (FSGS) can lead to ESRD requiring a renal transplant and the rate of recurrent FSGR (rFSGS) is high. The exact mechanisms of the pathogenesis of FSGS and rFSGS is unclear and both… read more here.
Keywords: transplant; angiotensin receptor; receptor type; renal transplant ... See more keywords
P1808INHIBITION OF MIR-155 IMPROVES PROGNOSIS IN AN EXPERIMENTAL FSGS MOUSE MODEL BY REGULATING AUTOPHAGY
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p1808
Abstract: Focal segmental glomerulosclerosis (FSGS), a podocytopathy, is one of the most common primary glomerular diseases causing end-stage renal disease in children. Its mechanisms remain unclear and the effective treatment lacks. MiR-155 is a typical multifunctional… read more here.
Keywords: p1808inhibition mir; mir 155; 155 improves; model ... See more keywords
Effect of cyclosporine A on focal segmental glomerulosclerosis caused by MYO1E mutation in a Chinese adult patient: A case report
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000032683
Abstract: Rationale: Focal segmental glomerulosclerosis (FSGS) describes a renal histologic lesion with diverse causes and pathogenicities. Monogenic abnormalities which are associated with impaired function of podocyte could result in FSGS. Most of genetic FSGS do not… read more here.
Keywords: focal segmental; myo1e mutation; caused myo1e; mutation ... See more keywords
FSGS ACTH Gel: Part of the Answer?
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DOI: 10.1097/tp.0000000000002321
Abstract: In this issue, T. Alhamad et al1 retrospectively reviewed 20 cases of posttransplant recurrent and de novo focal segmental glomerular sclerosis (FSGS) treated by an adrenocorticotropic hormone (ACTH) analogue gel.FSGS recurrence has been reported in… read more here.
Keywords: acth gel; acth; part answer; fsgs ... See more keywords
Advanced therapeutics in focal and segmental glomerulosclerosis
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DOI: 10.1111/nep.13463
Abstract: Focal segmental glomerulosclerosis (FSGS) is a glomerulonephritis with podocyte injury. The renal prognosis of FSGS is relative poor. The overall remission rate of the FSGS patients with nephrotic syndrome to immunosuppressive treatments was reported as… read more here.
Keywords: focal segmental; advanced therapeutics; treatment; segmental glomerulosclerosis ... See more keywords
The urgent need for more research on how to treat recurrent focal and segmental glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Transplantation"
DOI: 10.1111/petr.13215
Abstract: Renal transplantation is the therapy of choice for endstage renal disease (ESRD) in children and adolescents.1 Unfortunately, some diseases recur in the transplant, such as hyperoxaluria type I2 and focal and segmental glomerulosclerosis (FSGS).3 Whereas… read more here.
Keywords: recurrent fsgs; transplant; transplantation; fsgs ... See more keywords