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   Articles with "fshr" as a keyword



Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.11.053

Abstract: OBJECTIVE Chondrocytes express many kinds of hormone receptors. The function of Follicle stimulating hormone (FSH) in the ovary is mediated by FSH receptor (FSHR). FSH receptor (FSHR) is found in many non-ovarian tissues, however it… read more here.

Keywords: fshr; mouse chondrocytes; expression; fsh ... See more keywords

Abstract 2005: FSHR-mediated targeted delivery of paclitaxel immunoliposomes in receptor overexpressing ovarian cancer cells

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-2005

Abstract: The purpose of this study was to explore the Fabʹ fragment of anti-FSHR (Follicle Stimulating Hormone Receptor) antibody as a targeting ligand to graft on the surface of paclitaxel (PTX) liposomes (PLs) for site-specific drug… read more here.

Keywords: cancer cells; ovarian cancer; microscopy; fshr ... See more keywords

OR14-06 Structural Features and Functional Effects of the Follicle-stimulating Hormone Receptor (FSHR) Allosteric Agonist CAN1405 as Disclosed by In Silico and In Vitro studies

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recommendations! Published in 2025 at "Journal of the Endocrine Society"

DOI: 10.1210/jendso/bvaf149.1949

Abstract: Abstract Disclosure: A. Ulloa-Aguirre: None. E. Jardón-Valadez: None. T. Zariñán: None. R. Gutiérrez-Sagal: None. S. Nataraja: TocopheRx. H.N. Yu: CanWell Pharma Inc.. The FSHR plays an essential role in reproduction. Variations in the structure of… read more here.

Keywords: receptor; fshr; can1405; allosteric agonist ... See more keywords

SAT-656 Sex-Dependent Regulation of Body Composition by Adipocyte FSHR

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recommendations! Published in 2025 at "Journal of the Endocrine Society"

DOI: 10.1210/jendso/bvaf149.373

Abstract: Abstract Disclosure: G. Burganova: None. A. Gumerova: None. G. Pevnev: None. Z. Nakadar: None. P.T. Shyu: None. G.F. Guerriero: None. U. Cheliadinova: None. S.L. Sims: None. O. Moldavski: None. O. Barak: None. X.E. Guo: None.… read more here.

Keywords: mice; none; obesity; adipoq cre ... See more keywords

Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.

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recommendations! Published in 2018 at "Reproduction"

DOI: 10.1530/rep-18-0015

Abstract: Polycystic ovary syndrome, a common condition characterized by endocrine dysfunction, menstrual irregularity, anovulation and polycystic ovaries, affects 5-7% of reproductive-age women. RAB5B, which is identified by a genome-wide association study as a risk locus for… read more here.

Keywords: fshr; granulosa cells; polycystic ovary; granulosa ... See more keywords

Significance of FSHR and LHCGR gene polymorphisms on clinical outcomes in gonadotropin-releasing hormone antagonist protocol with freeze-all strategy: A case-control study

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recommendations! Published in 2024 at "International Journal of Reproductive Biomedicine"

DOI: 10.18502/ijrm.v22i7.16962

Abstract: Abstract Background Follicle-stimulating hormone receptor (FSHR) and luteinizing hormone/choriogonadotropin receptor (LHCGR) are integral to ovarian function, facilitating follicle development and maturation through their respective hormonal interactions. The influence of receptor polymorphisms on the outcomes of… read more here.

Keywords: follicle; polymorphisms clinical; lhcgr n312s; hormone ... See more keywords

Three-Dimensional Genome Interactions Identify Potential Adipocyte Metabolism-Associated Gene STON1 and Immune-Correlated Gene FSHR at the rs13405728 Locus in Polycystic Ovary Syndrome

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recommendations! Published in 2021 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2021.686054

Abstract: Background rs13405728 was identified as one of the most prevalent susceptibility loci for polycystic ovary syndrome (PCOS) in Han Chinese and Caucasian women. However, the target genes and potential mechanisms of the rs13405728 locus remain… read more here.

Keywords: rs13405728 locus; fshr; ston1; pcos ... See more keywords

Inadequate detection of the FSHR complicates future research on extragonadal FSHR localization

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recommendations! Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2023.1095031

Abstract: Introduction Recently, follicle stimulating hormone (FSH) through interaction with its receptor (FSHR) has been proposed to play a role in postmenopausal osteoporosis and cardiovascular disease, rather than the loss of estrogen. To explore this hypothesis,… read more here.

Keywords: anti fshr; extragonadal fshr; fshr; fshr localization ... See more keywords