Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Sport and Health Science"
DOI: 10.1016/j.jshs.2020.11.010
Abstract: Highlights • The secretion of skeletal muscle FSTL1 was stimulated by dynamic resistance exercise.• FSTL1 from skeletal muscle supplemented the insufficiency of cardiac FSTL1, which promoted myocardial angiogenesis and protected the heart from myocardial infarction.•… read more here.
Keywords: skeletal muscle; dynamic resistance; dip2a; angiogenesis ... See more keywords
BBS4 regulates the expression and secretion of FSTL1, a protein that participates in ciliogenesis and the differentiation of 3T3-L1
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DOI: 10.1038/s41598-017-10330-0
Abstract: Bardet-Biedl syndrome is a model ciliopathy. Although the characterization of BBS proteins has evidenced their involvement in cilia, extraciliary functions for some of these proteins are also being recognized. Importantly, understanding both cilia and cilia-independent… read more here.
Keywords: secretion; fstl1; fstl1 protein; differentiation 3t3 ... See more keywords
Follistatin-like 1 protects against hypoxia-induced pulmonary hypertension in mice
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DOI: 10.1038/srep45820
Abstract: Pulmonary hypertension (PH) remains a life-limiting disease characterized by pulmonary vascular remodelling due to aberrant proliferation and migration of pulmonary artery smooth muscle cells (PASMCs), thus leading to raised pulmonary arterial pressure and right ventricular… read more here.
Keywords: pulmonary hypertension; fstl1; mice; hypoxia induced ... See more keywords
Differential expression of FSTL1 and its correlation with the pathological process of periodontitis.
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DOI: 10.1111/jre.13275
Abstract: AIMS This study aimed to elucidate the alterations in Follistatin-like protein 1 (FSTL1) and its association with the pathological process of periodontitis. METHODS This study included 48 patients with periodontitis and 42 healthy controls. The… read more here.
Keywords: process periodontitis; periodontitis; fstl1; pathological process ... See more keywords
FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2
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DOI: 10.1136/gutjnl-2021-325150
Abstract: Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented. Herein, we aimed to characterise the roles of macrophage… read more here.
Keywords: function; liver fibrosis; fstl1; pkm2 ... See more keywords
The Correlation between FSTL1 Expression and Airway Remodeling in Asthmatics
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DOI: 10.1155/2017/7918472
Abstract: Background Asthma is characterized by airway remodeling. Follistatin-like protein 1 (FSTL1) is an extracellular glycoprotein. Recent studies suggest that FSTL1 may participate in the pathogenesis of asthma. Objectives To analyze the association between FSTL1 and… read more here.
Keywords: correlation fstl1; remodeling asthmatics; fstl1; fstl1 levels ... See more keywords
Abstract 5692: Distinct effectors of FSTL1 promote melanoma growth and angiogenesis and FSTL1 blockade mitigates resistance to BRAF and MEK inhibitors
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DOI: 10.1158/1538-7445.am2025-5692
Abstract: Melanoma is a highly lethal form of skin cancer due to its propensity for metastasis through angiogenesis, which confers melanoma initiating cells with resistance to BRAF and MEK inhibitors. However, current drugs for targeting angiogenesis… read more here.
Keywords: mek inhibitors; fstl1; braf mek; melanoma ... See more keywords
Follistatin-Like 1 and Family with Sequence Similarity to 19 Member A5 Levels Are Decreased in Obese Children and Associated with Glucose Metabolism
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DOI: 10.1159/000524624
Abstract: Introduction: Childhood obesity is a significant and growing problem worldwide. Recent evidence suggests Follistatin-like 1 (FSTL1) and family with sequence similarity to 19 member A5 (FAM19A5) to be novel adipokines. However, very few studies have… read more here.
Keywords: metabolism; obese children; fstl1; glucose metabolism ... See more keywords
Follistatin-like 1 (FSTL1) is a prognostic biomarker and correlated with immune cell infiltration in gastric cancer
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DOI: 10.1186/s12957-020-02070-9
Abstract: Background Follistatin-like 1 (FSTL1) plays a central role in the progression of tumor and tumor immunity. However, the effect of FSTL1 on the prognosis and immune infiltration of gastric cancer (GC) remains to be elucidated.… read more here.
Keywords: immune cell; fstl1; infiltration; cell infiltration ... See more keywords
THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma
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DOI: 10.1186/s12967-024-05116-8
Abstract: THOC7-AS1 and FSTL1 expression are frequently upregulated in cutaneous squamous cell carcinoma (cSCC). However, their molecular biological mechanisms remain elusive and their potential as therapeutic targets needs urgent exploration. Human tissue samples were used to… read more here.
Keywords: expression; fstl1; cutaneous squamous; thoc7 as1 ... See more keywords
Association between Plasma Follistatin-like Protein 1 Levels and the Presence and Severity of Coronary Artery Disease.
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DOI: 10.1536/ihj.21-203
Abstract: Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein known for its role in inflammation. However, plasma FSTL1 levels in patients with coronary artery disease (CAD) have not been fully elucidated. Thus, in this study, we… read more here.
Keywords: cad; disease; fstl1; protein ... See more keywords