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   Articles with "ftc taf" as a keyword



Pharmacokinetics of Tenofovir Alafenamide, Tenofovir, and Emtricitabine Following Administration of Coformulated Emtricitabine/Tenofovir Alafenamide in Healthy Japanese Subjects

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recommendations! Published in 2019 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.623

Abstract: A fixed‐dose combination of tenofovir alafenamide (TAF) and emtricitabine (FTC) is available in 2 tablet strengths in Japan (FTC/TAF 200/10 mg and FTC/TAF 200/25 mg). These are used once daily in combination with other antiretroviral… read more here.

Keywords: ftc taf; treatment; tenofovir alafenamide; taf 200 ... See more keywords

Comparison of the design and methodology of Phase 3 clinical trials of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) and dolutegravir-based dual therapy (DTG) in HIV: a systematic review of the literature

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recommendations! Published in 2022 at "Expert Review of Anti-infective Therapy"

DOI: 10.1080/14787210.2023.2149490

Abstract: ABSTRACT Introduction Current recommended antiretroviral regimens include a combination of two (dual; DT) or three (triple; TT) antiretroviral drugs. This study aims to determine whether the quality of evidence from clinical trials of dolutegravir (dolutegravir/lamivudine… read more here.

Keywords: clinical trials; methodology; ftc taf; bic ftc ... See more keywords

Randomized Trial Evaluating the Neurotoxicity of Dolutegravir/Abacavir/Lamivudine and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide: GESIDA 9016

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recommendations! Published in 2020 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofaa482

Abstract: Abstract Background Despite evidence shown of dolutegravir (DTG)-related neurotoxicity, which may be more common when combined with abacavir (ABC), its reversibility has not been explored in a clinical trial. Methods We conducted a randomized, multicenter,… read more here.

Keywords: ftc taf; cobi ftc; neuropsychiatric symptoms; evg cobi ... See more keywords

Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment-Experienced Patients

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recommendations! Published in 2021 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofaa625

Abstract: Abstract Background Switching antiretroviral therapy (ART) in people with HIV (PWH) can influence their risk for drug–drug interactions (DDIs). The purpose of this study was to assess changes in the incidence and severity of DDIs… read more here.

Keywords: bic ftc; ftc taf; drug; art ... See more keywords

Changes in blood lipid levels and influencing factors among treatment-naïve adult male HIV/AIDS patients following BIC/FTC/TAF vs. 3TC+EFV+TDF

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recommendations! Published in 2024 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000003147

Abstract: Abstract Background: Antiretroviral therapy (ART) was often associated with dyslipidemia among human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. This study aimed to assess treatment-naïve adult male patients with HIV/AIDS who initiated ART with either… read more here.

Keywords: treatment; ftc taf; 3tc efv; bic ftc ... See more keywords

Bictegravir/emtricitabine/tenofovir alafenamide plus doravirine in highly treatment-experienced men with multidrug-resistant HIV

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recommendations! Published in 2023 at "AIDS"

DOI: 10.1097/qad.0000000000003513

Abstract: Objective: To evaluate the safety and efficacy of switching highly treatment-experienced people with HIV (HTE PWH) from rilpivirine/emtricitabine/tenofovir alafenamide (RPV/FTC/TAF) plus dolutegravir (DTG) to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) plus doravirine (DOR). A pharmacokinetic (PK) analysis was… read more here.

Keywords: taf plus; emtricitabine tenofovir; ftc taf; treatment ... See more keywords

Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence In Vitro

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recommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.02038-21

Abstract: The integrase strand transfer inhibitor (INSTI)-based regimens bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF), dolutegravir (DTG)+FTC/TAF, DTG/lamivudine (3TC), and DTG/rilpivirine (RPV) are all approved for treatment of HIV-infected patients, with various limitations. Here, time to in vitro viral breakthrough… read more here.

Keywords: drug; resistance; ftc taf; dtg ... See more keywords

Switching to a Bictegravir Single Tablet Regimen in Elderly People Living with HIV-1: Data Analysis from the BICTEL Cohort

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recommendations! Published in 2021 at "Diagnostics"

DOI: 10.3390/diagnostics12010076

Abstract: Bictegravir/emtricitabine/tenofovir alafenamide fumarate (BIC/FTC/TAF) is a recommended once-daily single tablet regimen for the treatment of people living with HIV-1 (PLWH). We aimed to assess efficacy, safety and tolerability of BIC/FTC/TAF among PLWH, with a specific… read more here.

Keywords: single tablet; value; bic ftc; tablet regimen ... See more keywords