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Published in 2019 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.623
Abstract: A fixed‐dose combination of tenofovir alafenamide (TAF) and emtricitabine (FTC) is available in 2 tablet strengths in Japan (FTC/TAF 200/10 mg and FTC/TAF 200/25 mg). These are used once daily in combination with other antiretroviral…
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Keywords:
ftc taf;
treatment;
tenofovir alafenamide;
taf 200 ... See more keywords
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1
Published in 2022 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2023.2149490
Abstract: ABSTRACT Introduction Current recommended antiretroviral regimens include a combination of two (dual; DT) or three (triple; TT) antiretroviral drugs. This study aims to determine whether the quality of evidence from clinical trials of dolutegravir (dolutegravir/lamivudine…
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Keywords:
clinical trials;
methodology;
ftc taf;
bic ftc ... See more keywords
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Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa482
Abstract: Abstract Background Despite evidence shown of dolutegravir (DTG)-related neurotoxicity, which may be more common when combined with abacavir (ABC), its reversibility has not been explored in a clinical trial. Methods We conducted a randomized, multicenter,…
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Keywords:
ftc taf;
cobi ftc;
neuropsychiatric symptoms;
evg cobi ... See more keywords
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Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa625
Abstract: Abstract Background Switching antiretroviral therapy (ART) in people with HIV (PWH) can influence their risk for drug–drug interactions (DDIs). The purpose of this study was to assess changes in the incidence and severity of DDIs…
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Keywords:
bic ftc;
ftc taf;
drug;
art ... See more keywords
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2
Published in 2023 at "AIDS"
DOI: 10.1097/qad.0000000000003513
Abstract: Objective: To evaluate the safety and efficacy of switching highly treatment-experienced people with HIV (HTE PWH) from rilpivirine/emtricitabine/tenofovir alafenamide (RPV/FTC/TAF) plus dolutegravir (DTG) to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) plus doravirine (DOR). A pharmacokinetic (PK) analysis was…
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Keywords:
taf plus;
emtricitabine tenofovir;
ftc taf;
treatment ... See more keywords
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1
Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02038-21
Abstract: The integrase strand transfer inhibitor (INSTI)-based regimens bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF), dolutegravir (DTG)+FTC/TAF, DTG/lamivudine (3TC), and DTG/rilpivirine (RPV) are all approved for treatment of HIV-infected patients, with various limitations. Here, time to in vitro viral breakthrough…
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Keywords:
drug;
resistance;
ftc taf;
dtg ... See more keywords
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Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics12010076
Abstract: Bictegravir/emtricitabine/tenofovir alafenamide fumarate (BIC/FTC/TAF) is a recommended once-daily single tablet regimen for the treatment of people living with HIV-1 (PLWH). We aimed to assess efficacy, safety and tolerability of BIC/FTC/TAF among PLWH, with a specific…
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Keywords:
single tablet;
value;
bic ftc;
tablet regimen ... See more keywords