Pharmacokinetics of Co-encapsulated Antiretrovirals with Ingestible Sensors.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2019.0202
Abstract: We investigated the use of a system with an ingestible sensor (Proteus Digital Health Feedback system) co-encapsulated with antiretrovirals (ARVs) to measure real-time adherence. To assess the safety and impact, if any, co-encapsulation might have… read more here.
Keywords: encapsulated antiretrovirals; cmax; auc; ftc ... See more keywords
The effect of efavirenz on reward processing in asymptomatic people living with HIV: a randomized controlled trial.
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DOI: 10.1089/aid.2022.0069
Abstract: Functional MRI studies have demonstrated that HIV-infection affects the fronto-striatal network. It has not been examined what impact efavirenz, an antiretroviral drug notorious for its neurocognitive effects, has on the reward system: a key subcomponent… read more here.
Keywords: processing; effect; reward; ftc tdf ... See more keywords
Week 96 efficacy of lopinavir/ritonavir monotherapy in virologically suppressed patients with HIV: a randomized non-inferiority trial (ANRS 140 DREAM)
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DOI: 10.1093/jac/dky055
Abstract: Background Sparing of antiretroviral drug classes could reduce the toxicity and cost of maintenance treatment for HIV infection. Objectives To evaluate the non-inferiority of efficacy and the safety of lopinavir/ritonavir (r) monotherapy versus a single-tablet… read more here.
Keywords: week; ftc tdf; non inferiority; monotherapy ... See more keywords
Impact of Tenofovir-Based Pre-exposure Prophylaxis on Biomarkers of Bone Formation, Bone Resorption, and Bone Mineral Metabolism in HIV-Negative Adults
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DOI: 10.1093/ofid/ofz338
Abstract: Abstract Background Pre-exposure prophylaxis (PrEP) with emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) reduces the risk of HIV seroconversion but may promote bone mineral density (BMD) decline. The mechanisms of BMD decline with FTC/TDF remain unclear, and… read more here.
Keywords: bone mineral; ftc tdf; bone; tdf ... See more keywords
Virological Outcomes of EVG/COBI/FTC/TDF and EVG/COBI/FTC/TAF in Antiretroviral-Naive HIV-1-Infected Participants with Baseline HIV-1 RNA ≥1,000,000 Copies/ml: A Post Hoc Analysis of Phase III Clinical Trials
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Therapy"
DOI: 10.3851/imp3187
Abstract: We address a data gap identified by Adams et al. [1], of virological efficacy outcomes and emergent drug resistance in HIV-1-infected, antiretroviral treatment (ART)naive participants with baseline (BL) viral loads (VL) >1,000,000 copies/ml. Initial ART… read more here.
Keywords: ftc; ftc tdf; evg cobi; cobi ftc ... See more keywords
Análisis de coste-utilidad de la combinación a dosis fijas de dolutegravir/abacavir/lamivudina como tratamiento inicial de pacientes con VIH + en España
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DOI: 10.7399/fh.10808
Abstract: Objective: Fixed-dose combinations of antiretroviral drugs have meant an important step forward in simplifying treatment and improving compliance and has led to an increased effectiveness of therapy, a viral load decrease and improving the quality of life of… read more here.
Keywords: ftc tdf; treatment; fixed dose; abc 3tc ... See more keywords