Altered expression of costimulatory molecules in dementias
Sign Up to like & getrecommendations! Published in 2021 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-021-01297-1
Abstract: Although the expression of co-stimulatory molecules plays an important role in the immune system, only little is known about their regulation in dementias. Therefore, we determined the expression of CD28, ICOS (CD278) and CTLA-4 (CD152)… read more here.
Keywords: cd8 cells; cd28 icos; cd28; ftd patients ... See more keywords
Connectivity-based characterisation of subcortical grey matter pathology in frontotemporal dementia and ALS: a multimodal neuroimaging study
Sign Up to like & getrecommendations! Published in 2018 at "Brain Imaging and Behavior"
DOI: 10.1007/s11682-018-9837-9
Abstract: Frontotemporal dementia (FTD) phenotypes have distinctive and well-established cortical signatures, but their subcortical grey matter profiles are poorly characterised. The comprehensive characterisation of striatal and thalamic pathology along the ALS-FTD spectrum is particularly timely, as… read more here.
Keywords: grey matter; subcortical grey; pathology; ftd patients ... See more keywords
TREM2 variants in neurodegenerative disorders in the Polish population. Homozygosity and compound heterozygosity in FTD patients
Sign Up to like & getrecommendations! Published in 2018 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"
DOI: 10.1080/21678421.2018.1451894
Abstract: Abstract Activation of the TREM2 receptor on microglia stimulates phagocytosis and decreases the microglial proinflammatory response. Mutations in exon 2 of the TREM2 gene have been reported to be associated with various neurodegenerative diseases characterized… read more here.
Keywords: ftd; ftd patients; compound; polish population ... See more keywords
18 F-FDG PET, cortical thickness, and white matter graph network abnormalities in ALS-FTD patient brains suggest early neuronopathy rather than axonopathy.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of neurology"
DOI: 10.1111/ene.14332
Abstract: OBJECTIVE Amyotrophic lateral sclerosis (ALS) is a motor neuron disorder, although extramotor degeneration is well recognized, especially in frontotemporal regions manifest as ALS with frontotemporal dementia (ALS-FTD). Previous neuroimaging studies of brains of ALS-FTD patients… read more here.
Keywords: ftd patients; als ftd; cortical thickness; white matter ... See more keywords
Frontotemporal dementia and financial capacity: facing the Cerberus of overestimation or underestimation?
Sign Up to like & getrecommendations! Published in 2021 at "Australasian Psychiatry"
DOI: 10.1177/10398562211005444
Abstract: Objective: This study investigates the performance of people with frontotemporal dementia (FTD) on objective assessment of financial capacity with comparison to the estimation of financial capacity by both people themselves and their caregivers. Method: FTD… read more here.
Keywords: capacity; financial capacity; performance; frontotemporal dementia ... See more keywords