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FTLD/ALS-linked TDP-43 mutations do not alter TDP-43’s ability to self-regulate its expression in Drosophila

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1 Published in 2018 at "Brain Research"

DOI: 10.1016/j.brainres.2018.05.021

Abstract: TDP-43 is a major disease-causing protein in amyotrophic lateral sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD). Today, >50 missense mutations in the TARDBP/TDP-43 gene have been described in patients with FTLD/ALS. However, the functional consequences… read more here.

Keywords: protein; linked tdp; tdp mutations; als linked ... See more keywords