Up-regulation of FTO– gene expression was associated with increase in skeletal muscle mass in overweight male adolescents
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Nutrition"
DOI: 10.1016/j.clnu.2018.06.1124
Abstract: Introduction: The modifying effect of FTO gene expression level on change in body mass index and body composition has not been studied before. This study aimed to investigate the association between change in the expression… read more here.
Keywords: change; fto gene; gene expression; gene ... See more keywords
Association analysis of FTO gene polymorphisms with obesity in Greek adults.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.02.033
Abstract: Nowadays, obesity is the greatest scourge worldwide, particularly for the developed countries and is a huge burden for the public health. Over the past decade, GWAS have revealed a number of genes associated with obesity.… read more here.
Keywords: association; obesity; fto gene; obesity greek ... See more keywords
FTO Gene Affects Obesity and Breast Cancer Through Similar Mechanisms: A New Insight into the Molecular Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2018 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2018.1397709
Abstract: ABSTRACT Objectives: This review focused on the possible mediatory role of the FTO in the association between obesity and breast cancer. Method: All articles published in English from June 1990 to January 2017 were studied.… read more here.
Keywords: fto gene; breast cancer; cancer; obesity breast ... See more keywords
Unravelling the Complex Interactions Between the FTO Gene, Lifestyle, and Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in nutrition"
DOI: 10.1093/advances/nmac101
Abstract: Carcinogenesis as a complicated process originates from genetic, epigenetic, and environmental factors. Recent studies have reported a potential critical role for the fat mass and obesity-associated (FTO) gene in carcinogenesis through different signaling pathways such… read more here.
Keywords: fto gene; lifestyle cancer; unravelling complex; complex interactions ... See more keywords
The effects of FTO gene rs9939609 polymorphism on the association between breast cancer and dietary intake
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17595
Abstract: Breast cancer (BC) is the leading cause of cancer‐related deaths in females worldwide and is related to genetic and environmental factors. Dietary components may strongly influence the risk of BC. A possible association was also… read more here.
Keywords: fto gene; risk; association; dietary intake ... See more keywords
Cardiovascular Risk Factors after Childhood Cancer Treatment Are Independent of the FTO Gene Polymorphism?
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Endocrinology"
DOI: 10.1155/2018/7495234
Abstract: The study objective was to assess the prevalence of cardiovascular disease risk factors in patients treated for childhood cancer (N = 101) and to determine the involvement of clinical (cancer type and therapy) and/or genetic… read more here.
Keywords: polymorphism; fto gene; risk factors; cancer ... See more keywords
A complete linkage disequilibrium in a haplotype of three SNPs in Fat Mass and Obesity associated (FTO) gene was strongly associated with anthropometric indices after controlling for calorie intake and physical activity
Sign Up to like & getrecommendations! Published in 2018 at "BMC Medical Genetics"
DOI: 10.1186/s12881-018-0664-z
Abstract: BackgroundThe underlying mechanism of the effect of FTO genotype on body mass index (BMI) and body composition is unknown. The objective of the study was to investigate the association of FTO gene polymorphisms with anthropometric… read more here.
Keywords: intake physical; fto gene; calorie intake; physical activity ... See more keywords
[Association between FTO gene rs9939609 and adiposity markers in Chilean children].
Sign Up to like & getrecommendations! Published in 2020 at "Revista chilena de pediatria"
DOI: 10.32641/rchped.v91i3.1395
Abstract: INTRODUCTION Obesity is considered a chronic inflammatory disease with an important genetic component. Although several studies have reported an association between the FTO (fat-mass associated gene) and adiposity in children, there is limited evidence in… read more here.
Keywords: fto gene; chilean children; adiposity markers; gene ... See more keywords
Emerging Role and Mechanism of the FTO Gene in Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13050850
Abstract: The fat mass and obesity-associated (FTO) gene was the first obesity-susceptibility gene identified through a genome-wide association study (GWAS). A growing number of studies have suggested that genetic variants of FTO are strongly associated with… read more here.
Keywords: fto gene; cardiovascular diseases; emerging role; m6a ... See more keywords
Effects of Helicobacter pylori on the expression of the FTO gene and its biological role in gastric cancer
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Letters"
DOI: 10.3892/ol.2023.13729
Abstract: Helicobacter pylori (Hp) is a primary risk factor for gastric cancer. The fat mass and obesity-associated (FTO) gene is associated with the development and progression of various cancer types such as glioma, leukemia, breast cancer… read more here.
Keywords: fto gene; cancer; expression fto; gastric cancer ... See more keywords