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Published in 2019 at "Appetite"
DOI: 10.1016/j.appet.2019.104368
Abstract: BACKGROUND The fat mass and obesity-associated gene (FTO) rs9939609 A-allele has been associated with obesity risk. Although the exact mechanisms involved remain unknown, the FTO rs9939609 A-allele has been associated with an impaired postprandial suppression…
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Keywords:
postprandial appetite;
rs9939609 genotype;
fasting postprandial;
appetite related ... See more keywords
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Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.09.053
Abstract: BACKGROUND Fat mass and obesity-associated protein gene variants have shown diverse influence on body weight and metabolism across different populations. Overweight, obesity and metabolic syndrome are multifactorial major health problems in the UAE and worldwide.…
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Keywords:
insulin;
fto rs9939609;
fasting glucose;
insulin resistance ... See more keywords
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Published in 2022 at "Current Developments in Nutrition"
DOI: 10.1093/cdn/nzac014
Abstract: ABSTRACT Background Second-generation antipsychotics (SGAs) are used to treat children for mental health disorders but in some children they cause cardiometabolic complications including weight gain and type 2 diabetes. Genetic variants can place a child…
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Keywords:
health disorders;
fto rs9939609;
children mental;
mental health ... See more keywords
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Published in 2018 at "Medical Principles and Practice"
DOI: 10.1159/000486767
Abstract: Objective: To investigate the effect of the common fat mass and obesity-associated (FTO) gene polymorphism rs9939609 on body mass index (BMI) in one of the most obese populations worldwide. Subjects and Methods: Genotypic data for…
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Keywords:
association;
obesity kuwaiti;
obesity;
fto rs9939609 ... See more keywords
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Published in 2018 at "BMC Medical Genetics"
DOI: 10.1186/s12881-018-0668-8
Abstract: BackgroundGenetic and environmental factors play a crucial role in the development of type 2 diabetes mellitus (T2DM) and obesity. This study aimed to investigate the association of the fat-mass and obesity-associated gene (FTO) rs9939609 variant…
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Keywords:
rs9939609;
type diabetes;
rs9939609 variant;
fto rs9939609 ... See more keywords
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Published in 2020 at "Journal of Physiological Anthropology"
DOI: 10.1186/s40101-020-00224-y
Abstract: Background Fat mass and obesity-associated gene ( FTO ) is the most studied obesity-related gene up to date. We aimed to assess anthropometric indices in carriers of FTO rs9939609 polymorphism with overweight across Iranian population…
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Keywords:
anthropometric indices;
rs9939609 polymorphism;
obesity;
gene ... See more keywords
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Published in 2019 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s199542
Abstract: Background: Obesity occurs due to the interaction between the genetic background and environmental factors, including an increased food intake and a sedentary lifestyle. Nowadays, it is clear that there is a specific circuit, called leptin-melanocortin…
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Keywords:
severe obesity;
obesity;
polymorphism;
fat mass ... See more keywords
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Published in 2023 at "Diabetes care"
DOI: 10.2337/dc22-2078
Abstract: OBJECTIVE The association between FTO rs9939609 and obesity is modified by physical activity (PA) and/or insulin sensitivity (IS). We aimed to assess whether these modifications are independent, whether PA and/or IS modify the association between…
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Keywords:
rs9939609;
rs9939609 obesity;
fto;
insulin ... See more keywords
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Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.891819
Abstract: Background Gene polymorphisms may explain the controversy on the association between colorectal cancer (CRC) and dietary fibers. The purpose of this study was to investigate the effect of fat mass and obesity-associated (FTO) rs9939609 polymorphism…
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Keywords:
dietary fiber;
polymorphism;
fiber;
association ... See more keywords
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Published in 2023 at "Nutrients"
DOI: 10.3390/nu15092037
Abstract: The FTO rs9939609 gene, which presents three polymorphisms (AA, AT, and TT), has been associated with the development of obesity through an increased fat accumulation; however, the associations of the gene with other physiological mechanisms,…
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Keywords:
fto rs9939609;
young adults;
fat oxidation;
gene ... See more keywords