Orientation of FtsH protease homologs in Trypanosoma brucei inner mitochondrial membrane and its evolutionary implications.
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DOI: 10.1016/j.molbiopara.2020.111282
Abstract: Trypanosoma brucei is an important human pathogen. In this study, we have focused on the characterization of FtsH protease, ATP-dependent membrane-bound mitochondrial enzyme important for regulation of protein abundance. We have determined localization and orientation… read more here.
Keywords: protease; ftsh; orientation; mitochondrial membrane ... See more keywords
YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide
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DOI: 10.1128/mbio.00598-20
Abstract: Gram-negative bacteria are encapsulated by an outer membrane (OM) that is impermeable to large and hydrophobic molecules. As such, these bacteria are intrinsically resistant to several clinically relevant antibiotics. To better understand how the OM… read more here.
Keywords: membrane; activity; protease complex; ycim ftsh ... See more keywords