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Abstract 5610: [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-inhibitor drug-target engagement as a biomarker of response in ovarian cancer

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-5610

Abstract: Purpose: Poly(ADP-ribose) polymerase enzyme inhibitors (PARPi) have become the standard-of-care treatment for homologous recombination deficient (HRD) high-grade serous ovarian cancer (HGSOC). However, not all HRD tumors respond to PARPi and biomarkers to predict response are… read more here.

Keywords: ftt pet; response; cancer; parpi ... See more keywords