Repeatability of Scheimpflug Tomography for Assessing Fuchs Endothelial Corneal Dystrophy.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2020.02.004
Abstract: PURPOSE To determine if agreement between subjective interpretations of Scheimpflug tomography maps of corneas with Fuchs endothelial corneal dystrophy (FECD) is affected by daily and hourly changes in corneal edema. DESIGN Reliability analysis. METHODS Scheimpflug… read more here.
Keywords: agreement; images taken; scheimpflug tomography; fuchs endothelial ... See more keywords
Therapeutic contact lens for Fuchs endothelial corneal dystrophy: Monitoring with Scheimpflug tomography
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2021.101242
Abstract: Purpose This case report demonstrates the effectiveness of a combined unique soft contact lens design and hypertonic saline at reducing corneal edema symptoms. In addition, this case shows that using tomographic data is invaluable for… read more here.
Keywords: contact lens; fuchs endothelial; contact; monitoring ... See more keywords
TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2020.100883
Abstract: Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in the elderly. Since the first description of an association between FECD and common polymorphisms situated within the transcription factor 4 (TCF4)… read more here.
Keywords: expansion; fuchs endothelial; repeat; disease ... See more keywords
Risk factors for corneal transplantation in Fuchs endothelial corneal dystrophy from a large Thai cohort
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DOI: 10.1038/s41598-025-26423-0
Abstract: This study aimed to identify risk factors associated with corneal transplantation within five years among Thai patients with Fuchs endothelial corneal dystrophy (FECD) and to evaluate whether isolated cataract surgery could defer the need for… read more here.
Keywords: corneal transplantation; transplantation; risk factors; fuchs endothelial ... See more keywords
Comprehensive analysis of splicing variants in corneal endothelial cells of patients with Fuchs endothelial corneal dystrophy
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DOI: 10.1038/s41598-025-92119-0
Abstract: Trinucleotide repeat (TNR) expansion in the transcription factor 4 (TCF4) gene represents the most prevalent genetic risk factor for Fuchs endothelial corneal dystrophy (FECD) and may cause dysfunction of splicing regulators. We investigated differential alternative… read more here.
Keywords: corneal dystrophy; endothelial corneal; analysis; fuchs endothelial ... See more keywords
Descemet Stripping without Transplantation in Fuchs Endothelial Corneal Dystrophy.
Sign Up to like & getrecommendations! Published in 2022 at "Klinische Monatsblatter fur Augenheilkunde"
DOI: 10.1055/a-1751-3411
Abstract: Traditionally, corneal endothelium is considered post-mitotic, which means that spontaneous regeneration after loss of endothelial cells (e.g., in the context of Fuchs endothelial corneal dystrophy) is not expected. Nevertheless, it has been observed in several… read more here.
Keywords: endothelial corneal; descemet stripping; fuchs endothelial; corneal ... See more keywords
Predictive Factors for Clinical Outcomes after Primary Descemet’s Membrane Endothelial Keratoplasty for Fuchs’ Endothelial Dystrophy
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DOI: 10.1080/02713683.2018.1538459
Abstract: ABSTRACT Purpose: The purpose of this study is to identify predictors for the best-corrected visual acuity (BCVA), central corneal thickness (CCT), and the endothelial cell density (ECD) after primary Descemet’s membrane endothelial keratoplasty (DMEK). Methods:… read more here.
Keywords: fuchs endothelial; dystrophy; primary descemet; membrane endothelial ... See more keywords
Parents of Patients With Congenital Hereditary Endothelial Dystrophy Should Be Evaluated for Fuchs Endothelial Corneal Dystrophy.
Sign Up to like & getrecommendations! Published in 2017 at "Cornea"
DOI: 10.1097/ico.0000000000001397
Abstract: To the Editor: Congenital hereditary endothelial dystrophy (CHED) and Fuchs endothelial corneal dystrophy (FECD) are the 2 common types of endothelial dystrophy seen in the Indian population. Several genes have been implicated as playing a… read more here.
Keywords: corneal; fuchs endothelial; dystrophy; congenital hereditary ... See more keywords
A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
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DOI: 10.1097/ico.0000000000002642
Abstract: Abstract: The current understanding on the clinical efficacy of Rho-associated protein kinase (ROCK) inhibitor for treating Fuchs endothelial corneal dystrophy is summarized to clarify whether the “off-label” ROCK-inhibitor eye-drop application are appropriate. ROCK-inhibitor eye drops… read more here.
Keywords: inhibitor eye; corneal dystrophy; endothelial corneal; inhibitor ... See more keywords
Descemet Stripping Without Endothelial Keratoplasty in Early-Stage Central Fuchs Endothelial Dystrophy: Long-term Results.
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DOI: 10.1097/ico.0000000000003131
Abstract: PURPOSE The purpose of this study was to report long-term results of Descemet stripping without endothelial keratoplasty (DWEK) associated with phacoemulsification in patients with early-stage central Fuchs endothelial corneal dystrophy. METHODS This is a retrospective… read more here.
Keywords: endothelial keratoplasty; central fuchs; early stage; stage central ... See more keywords
Association between Fuchs Endothelial Corneal Dystrophy, Diabetes Mellitus and Multimorbidity
Sign Up to like & getrecommendations! Published in 2022 at "Cornea"
DOI: 10.1101/2022.12.14.22283472
Abstract: Purpose: To assess risk for demographic variables and other health conditions that are associated with Fuchs endothelial corneal dystrophy (FECD). Methods: We developed a FECD case-control algorithm based on structured EHR data and accuracy confirmed… read more here.
Keywords: fecd; endothelial corneal; fuchs endothelial; risk ... See more keywords