Enantioselective Copper-Catalyzed Fukuyama Indole Synthesis from 2-Vinylphenyl Isocyanides.
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DOI: 10.1021/jacs.3c01667
Abstract: Enantioenriched chiral indoles are of high interest for the pharmaceutical and agrochemical industries. Herein, we present an asymmetric Fukuyama indole synthesis through a mild and efficient radical cascade reaction to access 2-fluoroalkylated 3-(α-cyanobenzylated) indoles by… read more here.
Keywords: indole synthesis; fukuyama indole; synthesis; enantioselective copper ... See more keywords