Modulated podosome patterning in osteoclasts by fullerenol nanoparticles disturbs the bone resorption for osteoporosis treatment.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr01625j
Abstract: Overactivation and excessive differentiation of osteoclasts (OCs) has been implicated in the course of bone metabolism-related diseases. Although fullerenol nanoparticles (fNPs) have been suggested to inhibit OC differentiation and OC function in our previous work,… read more here.
Keywords: fullerenol nanoparticles; treatment; bone; modulated podosome ... See more keywords
The antihyperlipidemic effects of fullerenol nanoparticles via adjusting the gut microbiota in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Particle and Fibre Toxicology"
DOI: 10.1186/s12989-018-0241-9
Abstract: BackgroundNanoparticles (NPs) administered orally will meet the gut microbiota, but their impacts on microbiota homeostasis and the consequent physiological relevance remain largely unknown. Here, we describe the modulatory effects and the consequent pharmacological outputs of… read more here.
Keywords: fullerenol nanoparticles; microbiota; antihyperlipidemic effects; gut microbiota ... See more keywords