A Fully Synthetic Transcriptional Platform for a Multicellular Eukaryote.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2016.12.025
Abstract: Regions of genomic DNA called enhancers encode binding sites for transcription factor proteins. Binding of activators and repressors increase and reduce transcription, respectively, but it is not understood how combinations of activators and repressors generate… read more here.
Keywords: synthetic transcriptional; transcription; transcriptional platform; fully synthetic ... See more keywords
A fully synthetic lung model for wound-ballistic experiments-First results.
Sign Up to like & getrecommendations! Published in 2017 at "Forensic science international"
DOI: 10.1016/j.forsciint.2017.03.024
Abstract: PURPOSE Today, synthetic models have all but replaced animal and corpse models in examining damage to soft-tissues and skeletal structures by ballistic trauma. As, however, non-solid organs such as the lungs, have not been able… read more here.
Keywords: ballistic experiments; lung model; fully synthetic; model ... See more keywords
Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical biology"
DOI: 10.1021/acschembio.7b01057
Abstract: Studies on the polymerization mode of Neisseria meningitidis serogroup X capsular polymerase CsxA recently identified a truncated construct that can be immobilized and used for length controlled on-column production of oligosaccharides. Here, we combined the… read more here.
Keywords: combined chemical; fully synthetic; elongation; meningitidis serogroup ... See more keywords
SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate
Sign Up to like & getrecommendations! Published in 2024 at "NPJ Vaccines"
DOI: 10.1038/s41541-024-01046-0
Abstract: In the aim of designing and developing a novel saponin-based adjuvant system, we combined the QS21 saponin with low microgram amounts of the fully synthetic TLR4 agonist, E6020, in cholesterol-containing liposomes. The resulting adjuvant system,… read more here.
Keywords: adjuvant system; fully synthetic; synthetic tlr4; spa14 ... See more keywords
The feasibility of a fully synthetic and self-assembled peptide solution as submucosal injection material: a preliminary animal study
Sign Up to like & getrecommendations! Published in 2021 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2021.1934727
Abstract: Abstract Background and aim An injection solution is required to create a submucosal cushion (SMC) for safe endoscopic resection procedures. The aim of this preliminary animal study was to clarify the safety and efficacy of… read more here.
Keywords: preliminary animal; fully synthetic; submucosal; solution ... See more keywords
Comparative Analysis of Animal-Derived vs Fully Synthetic Acellular Dermal Matrices in Reconstructive Surgery
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000003909
Abstract: Introduction The fully synthetic skin substitute, NovoSorb Biodegradable Temporizing Matrix (BTM), may be a cost-effective alternative to the animal-derived Integra Dermal Regeneration Template (IDRT). However, the current literature insufficiently compares the two. Therefore, our study… read more here.
Keywords: compared idrt; animal derived; biodegradable temporizing; temporizing matrix ... See more keywords
Iterative Application of UMAP-Based Algorithms for Fully Synthetic Healthcare Tabular Data Generation
Sign Up to like & getrecommendations! Published in 2024 at "Algorithms"
DOI: 10.3390/a17120591
Abstract: Building on a previously developed partially synthetic data generation algorithm utilizing data visualization techniques, this study extends the novel algorithm to generate fully synthetic tabular healthcare data. In this enhanced form, the algorithm serves as… read more here.
Keywords: umap based; synthetic healthcare; healthcare; fully synthetic ... See more keywords