Combination of fulvestrant and chemotherapy in ESR1 Y537S mutant breast cancer cells and potential synergy mechanism related to p53 wildtype.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.1065
Abstract: 1065Background: The acquisition of ligand-independent ESR1 mutations during endocrine therapy in metastatic ER+ breast cancer is a common mechanism of resistance to endocrine treatment, particularl... read more here.
Keywords: combination fulvestrant; mechanism; breast; breast cancer ... See more keywords
The use of fulvestrant before chemotherapy improves survival in hormone-positive breast cancer: a real-life study.
Sign Up to like & getrecommendations! Published in 2022 at "Turkish journal of medical sciences"
DOI: 10.55730/1300-0144.5495
Abstract: BACKGROUND We aimed to evaluate the efficacy of fulvestrant and its affecting clinical factors, including the optimal sequencing of fulvestrant and chemotherapy in a real-life cohort. METHODS The data of 256 metastatic hormone-positive breast cancer… read more here.
Keywords: hormone positive; fulvestrant chemotherapy; real life; breast cancer ... See more keywords