Fumarate-based drugs protect against neuroinflammation via upregulation of anti-ferroptotic pathways
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DOI: 10.1186/s12974-025-03592-3
Abstract: Ferroptosis is defined as iron dependent non-apoptotic cell death. It is based on peroxidation of polyunsaturated phospholipids and subsequent membrane rupture. Lipid peroxidation is induced mainly by the hydroxyl radical, the product of the Fenton… read more here.
Keywords: based drugs; protect neuroinflammation; neuroinflammation; fumarate based ... See more keywords