Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis
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DOI: 10.1128/aac.01428-22
Abstract: Ascofuranone (AF), a meroterpenoid isolated from various filamentous fungi, including Acremonium egyptiacum, has been reported as a potential lead candidate for drug development against parasites and cancer. In this study, we demonstrated that AF and… read more here.
Keywords: dual inhibitors; potential lead; fumarate respiration; reductase ... See more keywords