Hyperglycemia suppresses the regulatory effect of hypoxia inducible factor-1α in pulmonary Aspergillus fumigatus infection.
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DOI: 10.1093/femspd/ftaa038
Abstract: Aspergillus fumigatus (A. fumigatus) is one of the most common fungal involved in the pulmonary diseases. Hypoxia inducible factor-1α (HIF-1α) is important for antifungal immunity. Diabetes is a risk factor of pulmonary A. fumigatus infection… read more here.
Keywords: fumigatus; hif; fumigatus infection; pulmonary fumigatus ... See more keywords
Biotinylated Surfome Profiling Identifies Potential Biomarkers for Diagnosis and Therapy of Aspergillus fumigatus Infection
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DOI: 10.1128/msphere.00535-20
Abstract: Aspergillus fumigatus is the most important airborne human-pathogenic mold, capable of causing both life-threatening invasive pulmonary aspergillosis in immunocompromised patients and allergy-inducing infections in individuals with atopic allergy. Despite its obvious medical relevance, timely diagnosis… read more here.
Keywords: surface; exposed regions; surface proteins; aspergillus fumigatus ... See more keywords
Primary cutaneous Aspergillus fumigatus infection in immunocompetent host
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DOI: 10.1136/bcr-2019-233020
Abstract: Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were… read more here.
Keywords: aspergillus fumigatus; cutaneous aspergillosis; fumigatus infection; cutaneous aspergillus ... See more keywords
Succinylation modification provides new insights for the treatment of immunocompromised individuals with drug-resistant Aspergillus fumigatus infection
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DOI: 10.3389/fimmu.2023.1161642
Abstract: Invasive Aspergillus fumigatus infection poses a serious threat to global human health, especially to immunocompromised individuals. Currently, triazole drugs are the most commonly used antifungals for aspergillosis. However, owing to the emergence of drug-resistant strains,… read more here.
Keywords: fumigatus infection; succinylation; aspergillus fumigatus; fumigatus ... See more keywords