Azole Resistance in Veterinary Clinical Aspergillus fumigatus Isolates in the Netherlands
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DOI: 10.1007/s11046-024-00850-5
Abstract: Aspergillus fumigatus is a saprophytic fungal pathogen that causes opportunistic infections in animals and humans. Azole resistance has been reported globally in human A. fumigatus isolates, but the prevalence of resistance in isolates from animals… read more here.
Keywords: resistance; azole resistance; azole resistant; aspergillus fumigatus ... See more keywords
Antifungal Susceptibility Tests and the cyp51 Mutant Strains among Clinical Aspergillus fumigatus Isolates from Korean Multicenters
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DOI: 10.1080/12298093.2020.1744955
Abstract: Abstract We investigated the antifungal susceptibilities and the cyp51 mutant strains among Aspergillus fumigatus clinical isolates obtained from 10 university hospitals in Korea. Of the 84 isolates examined, two itraconazole-resistant isolates were found with no… read more here.
Keywords: fumigatus isolates; aspergillus fumigatus; strains among; mutant strains ... See more keywords
Isolation of azole‐resistant Aspergillus fumigatus from the environment in the south‐eastern USA
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DOI: 10.1093/jac/dkx168
Abstract: Background: Azole resistance in isolates of the fungus Aspergillus fumigatus has been associated with agricultural use of azole fungicides. Environmental isolation of resistant isolates has been reported in Asia, Africa, Europe and South America. Objectives:… read more here.
Keywords: fumigatus; aspergillus fumigatus; fumigatus isolates; azole resistant ... See more keywords
Genomic description of human clinical Aspergillus fumigatus isolates, California, 2020
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DOI: 10.1093/mmy/myad012
Abstract: Abstract Aspergillus fumigatus, an environmental mold, causes life-threatening infections. Studies on the phylogenetic structure of human clinical A. fumigatus isolates are limited. Here, we performed whole genome sequencing of 24 A. fumigatus isolates collected from… read more here.
Keywords: genomic description; fumigatus isolates; aspergillus fumigatus; fumigatus ... See more keywords
Evidence of unique genetic diversity in Aspergillus fumigatus isolates from Cameroon
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DOI: 10.1111/myc.12655
Abstract: Aspergillus fumigatus is a saprophytic fungus that can cause lethal invasive aspergillosis in immunocompromised patients. Recent studies have shown that Eurasian and North American populations of A. fumigatus often consist of genetically diverse strains. However,… read more here.
Keywords: fumigatus; aspergillus fumigatus; fumigatus isolates; genetic diversity ... See more keywords
Antifungal Susceptibility and Genotypic Analysis of cyp51A Mutations in Aspergillus fumigatus Isolates in Malaysia
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DOI: 10.2147/idr.s452619
Abstract: Purpose Azole resistance in Aspergillus fumigatus poses a significant challenge in the management of invasive aspergillosis. This study aimed to investigate the antifungal susceptibility and cyp51A mutation profiles of A. fumigatus isolates in Malaysia. Patients… read more here.
Keywords: resistance; cyp51a mutations; antifungal susceptibility; aspergillus fumigatus ... See more keywords
Current Status of Azole-resistant Aspergillus fumigatus Isolates in East Asia.
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DOI: 10.3314/mmj.18.010
Abstract: Aspergillus fumigatus is a saprophytic fungus that is a major causative pathogen for aspergillosis. Only a few classes of antifungals are used for treating this life-threatening fungal infection. Azoles are the first-line drugs and are… read more here.
Keywords: fumigatus isolates; aspergillus fumigatus; azole; azole resistant ... See more keywords
Pulmonary Aspergillosis in Humboldt Penguins—Susceptibility Patterns and Molecular Epidemiology of Clinical and Environmental Aspergillus fumigatus Isolates from a Belgian Zoo, 2017–2022
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DOI: 10.3390/antibiotics12030584
Abstract: Aspergillus fumigatus is the main causative agent of avian aspergillosis and results in significant health problems in birds, especially those living in captivity. The fungal contamination by A. fumigatus in the environment of Humboldt penguins… read more here.
Keywords: fumigatus isolates; epidemiology; humboldt penguins; aspergillosis ... See more keywords
Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates
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DOI: 10.3390/jof4030103
Abstract: Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR34/L98H and TR46/Y121F/T289A are the two most common mutations associated with environmental resistance selection. We studied the… read more here.
Keywords: fumigatus isolates; aspergillus fumigatus; tr34 l98h; tr46 y121f ... See more keywords