TSLP‐activated dendritic cells induce T helper type 2 inflammation in Aspergillus fumigatus keratitis
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2018.03.014
Abstract: Abstract Thymic stromal lymphopoietin (TSLP) is an IL‐7‐like cytokine, which is secreted by epithelial cells under the stimulation of Toll‐like receptor (TLR) ligands. Dendritic cells (DCs) which express the thymic stromal lymphopoietin receptor (TSLPR) can… read more here.
Keywords: aspergillus fumigatus; fumigatus keratitis; inflammation; keratitis tslp ... See more keywords
Lipoxin A4 activates ALX/FPR2 to attenuate inflammation in Aspergillus fumigatus keratitis.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107785
Abstract: PURPOSE To explore the anti-inflammatory effect of lipoxin A4 (LXA4) in Aspergillus fumigatus (A. fumigatus) keratitis and the underlying mechanisms. METHODS In A. fumigatus keratitis mouse models, enzyme-linked immunosorbent assay (ELISA) was used to detect… read more here.
Keywords: anti inflammatory; fumigatus; aspergillus fumigatus; fumigatus keratitis ... See more keywords
Perillaldehyde Protects Against Aspergillus fumigatus Keratitis by Reducing Fungal Load and Inhibiting Inflammatory Cytokines and LOX-1
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2022.2093382
Abstract: Abstract Purpose The purpose of this research was to explore the antifungal and anti-inflammatory effects of perillaldehyde (PAE) in Aspergillus fumigatus (A. fumigatus) keratitis and the underlying mechanism. Methods The biofilm formation, adherence assay, and… read more here.
Keywords: fumigatus keratitis; aspergillus fumigatus; inflammatory cytokines; keratitis reducing ... See more keywords
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis
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DOI: 10.1097/ico.0000000000001756
Abstract: Purpose: Fungal keratitis is a major cause of corneal ulcers, resulting in significant visual impairment and blindness. Fenretinide, a derivative of vitamin A, has been shown to suppress inflammation in a multitude of diseases. In… read more here.
Keywords: aspergillus fumigatus; production; fumigatus keratitis; neutrophil recruitment ... See more keywords
Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis by reducing fungal load and inhibiting Mincle signal pathway
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1119568
Abstract: Aspergillus fumigatus keratitis is a potential blinding disease associated with A. fumigatus invasion and excessive inflammatory response. Benzyl isothiocyanate (BITC) is a secondary metabolite with broad antibacterial and anti-inflammatory activity extracted from cruciferous species. However,… read more here.
Keywords: fumigatus keratitis; aspergillus fumigatus; fumigatus; fungal load ... See more keywords
Thymol Ameliorates Aspergillus fumigatus Keratitis by Downregulating the TLR4/ MyD88/ NF-kB/ IL-1β Signal Expression and Reducing Necroptosis and Pyroptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Microbiology and Biotechnology"
DOI: 10.4014/jmb.2207.07017
Abstract: Fungal keratitis is a refractory kind of keratopathy. We attempted to investigate the anti-inflammatory role of thymol on Aspergillus fumigatus (A. fumigatus) keratitis. Wound healing and fluorescein staining of the cornea were applied to verify… read more here.
Keywords: fumigatus keratitis; aspergillus fumigatus; thymol; tlr4 myd88 ... See more keywords