Chemistry, structure and function of approved oligonucleotide therapeutics
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DOI: 10.1093/nar/gkad067
Abstract: Abstract Eighteen nucleic acid therapeutics have been approved for treatment of various diseases in the last 25 years. Their modes of action include antisense oligonucleotides (ASOs), splice-switching oligonucleotides (SSOs), RNA interference (RNAi) and an RNA… read more here.
Keywords: function approved; chemistry structure; structure function; chemistry ... See more keywords