Regulating Protein Function by Delayed Folding.
Sign Up to like & getrecommendations! Published in 2018 at "Structure"
DOI: 10.1016/j.str.2018.04.011
Abstract: In this issue of Structure, Tsirigotaki et al. (2018) use bioinformatics and biophysical tools to demonstrate that many secreted proteins form long-lived, loosely packed folding intermediates. This delayed folding correlates with elevated disorder and reduced hydrophobicity… read more here.
Keywords: protein function; function delayed; delayed folding; regulating protein ... See more keywords
Impaired function and delayed regeneration of dendritic cells in COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009742
Abstract: Disease manifestations in COVID-19 range from mild to severe illness associated with a dysregulated innate immune response. Alterations in function and regeneration of dendritic cells (DCs) and monocytes may contribute to immunopathology and influence adaptive… read more here.
Keywords: covid patients; impaired function; dendritic cells; regeneration dendritic ... See more keywords