C-RAF function at the genome-wide transcriptome level: A systematic view.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.02.034
Abstract: C-RAF was the first member of the RAF kinase family to be discovered. Since its discovery, C-RAF has been found to regulate many fundamental cell processes, such as cell proliferation, cell death, and metabolism. However,… read more here.
Keywords: view raf; raf function; function genome; raf ... See more keywords
A sequence-based method to predict the impact of regulatory variants using random forest
Sign Up to like & getrecommendations! Published in 2017 at "BMC Systems Biology"
DOI: 10.1186/s12918-017-0389-1
Abstract: BackgroundMost disease-associated variants identified by genome-wide association studies (GWAS) exist in noncoding regions. In spite of the common agreement that such variants may disrupt biological functions of their hosting regulatory elements, it remains a great… read more here.
Keywords: risk; impact; function genome; method ... See more keywords