Substrate stiffness affects the immunosuppressive and trophic function of hMSCs via modulating cytoskeletal polymerization and tension.
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DOI: 10.1039/c9bm01202h
Abstract: Mesenchymal stem cells (MSCs) have broad therapeutic potential due to their ability to secrete bioactive factors that are immunomodulatory and trophic (regenerative). In this study, polyacrylamide (PAAm) hydrogels with different stiffness are used as a… read more here.
Keywords: stiffness; function hmscs; immunosuppressive trophic; substrate stiffness ... See more keywords