Hyperuricemia and endothelial function: From molecular background to clinical perspectives.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.10.007
Abstract: Uric acid is the end product of purine metabolism catalyzed by xanthine oxidase in humans. In the process of purine metabolism, reactive oxygen species, including superoxide, are generated concomitantly with uric acid production, which may… read more here.
Keywords: endothelial dysfunction; uric acid; function molecular; endothelial function ... See more keywords
The Hsp60 protein of helicobacter pylori displays chaperone activity under acidic conditions
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2016.11.011
Abstract: The heat shock protein, Hsp60, is one of the most abundant proteins in Helicobacter pylori. Given its sequence homology to the Escherichia coli Hsp60 or GroEL, Hsp60 from H. pylori would be expected to function… read more here.
Keywords: hsp60 pylori; function molecular; acidic conditions; helicobacter pylori ... See more keywords
Biological function and molecular mechanism of piRNA in cancer
Sign Up to like & getrecommendations! Published in 2019 at "Practical Laboratory Medicine"
DOI: 10.1016/j.plabm.2018.e00113
Abstract: Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer genomics. In recent years, a relatively large number… read more here.
Keywords: pirna cancer; biological function; function molecular; molecular mechanism ... See more keywords
Generalized Green's function molecular dynamics for canonical ensemble simulations.
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review E"
DOI: 10.1103/physreve.97.053310
Abstract: The need of small integration time steps (∼1 fs) in conventional molecular dynamics simulations is an important issue that inhibits the study of physical, chemical, and biological systems in real timescales. Additionally, to simulate those systems… read more here.
Keywords: technique; molecular dynamics; green function; function molecular ... See more keywords
Structure, Function, and Molecular Landscapes of the Aging Retina.
Sign Up to like & getrecommendations! Published in 2023 at "Annual review of vision science"
DOI: 10.1146/annurev-vision-112122-020950
Abstract: Because the central nervous system is largely nonrenewing, neurons and their synapses must be maintained over the lifetime of an individual to ensure circuit function. Age is a dominant risk factor for neural diseases, and… read more here.
Keywords: system; function; function molecular; structure function ... See more keywords
N6-Methyladenosine RNA-Binding Protein YTHDF1 in Gastrointestinal Cancers: Function, Molecular Mechanism and Clinical Implication
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14143489
Abstract: Simple Summary N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA and plays a crucial role in the occurrence and development of diseases. YTHDF1 is the most powerful and abundant m6A-encoded RNA reader.… read more here.
Keywords: gastrointestinal cancers; function molecular; ythdf1; m6a ... See more keywords
Structural Determination, Biological Function, and Molecular Modelling Studies of Sulfoaildenafil Adulterated in Herbal Dietary Supplement
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26040949
Abstract: Unapproved ingredients included in herbal medicines and dietary supplements have been detected as adulterated synthetic drugs used for erectile dysfunction. Extraction from a dietary supplement was performed to isolate the compounds by HPLC analysis. The… read more here.
Keywords: determination biological; supplement; biological function; dietary supplement ... See more keywords