Piperlongumine activates Sirtuin1 and improves cognitive function in a murine model of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2018.02.002
Abstract: Abstract Sirtuin1 (Sirt1) is an unusual target for aging and aging-associated diseases. During the screening for Sirt1 activators from natural compounds, piperlongumine (PL), one of the major constituents of Piper longum, potently activated the deacetylase… read more here.
Keywords: function murine; sirtuin1 improves; piperlongumine activates; improves cognitive ... See more keywords
Ontogeny and function of murine epidermal Langerhans cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3815
Abstract: Langerhans cells (LCs) are epidermis-resident antigen-presenting cells that share a common ontogeny with macrophages but function as dendritic cells (DCs). Their development, recruitment and retention in the epidermis is orchestrated by interactions with keratinocytes through… read more here.
Keywords: ontogeny function; murine epidermal; function murine; immunology ... See more keywords