Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis
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DOI: 10.3390/ijms20246197
Abstract: The p53 protein is mutated in about 50% of human cancers. Aside from losing the tumor-suppressive functions of the wild-type form, mutant p53 proteins often acquire inherent, novel oncogenic functions, a phenomenon termed mutant p53… read more here.
Keywords: oncogenic functions; mutant p53; p53; gain function ... See more keywords