A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver
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DOI: 10.1186/s12915-022-01262-x
Abstract: Background Understanding the contribution of gene function in distinct organ systems to the pathogenesis of human diseases in biomedical research requires modifying gene expression through the generation of gain- and loss-of-function phenotypes in model organisms,… read more here.
Keywords: expression; mouse liver; function phenotypes; technology ... See more keywords
Heterogeneity of Lung Function Phenotypes in Sarcoidosis: Role of Race and Sex Differences.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the American Thoracic Society"
DOI: 10.1513/annalsats.202204-328oc
Abstract: RATIONALE Historically sarcoidosis was described as a restrictive lung disease, but several alternative phenotypes of pulmonary function have been observed. Pulmonary function phenotypes in sarcoidosis may represent different clinical and/or molecular phenotypes. OBJECTIVE To characterize… read more here.
Keywords: pulmonary function; function; phenotypes sarcoidosis; function phenotypes ... See more keywords