Detection of phenotype‐specific therapeutic vulnerabilities in breast cells using a CRISPR loss‐of‐function screen
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12951
Abstract: Cellular phenotype plasticity between the epithelial and mesenchymal states has been linked to metastasis and heterogeneous responses to cancer therapy, and remains a challenge for the treatment of triple‐negative breast cancer (TNBC). Here, we used… read more here.
Keywords: phenotype; loss function; function screen; phenotype specific ... See more keywords
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16517-w
Abstract: Chronic HBV infection is a major cause of liver disease and cancer worldwide. Approaches for cure are lacking, and the knowledge of virus-host interactions is still limited. Here, we perform a genome-wide gain-of-function screen using… read more here.
Keywords: hbv; function screen; host factor; host ... See more keywords
Crosstalk Suppressed 3D Light Field Display Based on an Optimized Holographic Function Screen
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DOI: 10.3390/mi13122106
Abstract: A holographic function screen (HFS) can recompose the wavefront and re-modulate the light-field distribution from a three-dimensional (3D) light field display (LFD) system. However, the spread function of existing HFSs does not particularly suit integral… read more here.
Keywords: light field; function; function screen; holographic function ... See more keywords