Assessing Mitochondrial Function in In Vitro and Ex Vivo Models of Huntington's Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7825-0_19
Abstract: Mitochondrial dysfunction has gained a preponderant role in the pathogenesis of Huntington's disease (HD). Mutant huntingtin (mHTT) directly interacts with mitochondria in a deleterious manner. As the central hub of the cell, not only mitochondrial… read more here.
Keywords: assessing mitochondrial; mitochondrial function; huntington disease; function vitro ... See more keywords
Assays of CFTR Function In Vitro, Ex Vivo and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031437
Abstract: Cystic fibrosis, a multi-organ genetic disease, is characterized by abnormal function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride channel at the apical membrane of several epithelia. In recent years, therapeutic strategies… read more here.
Keywords: function vitro; vivo; function; vivo vivo ... See more keywords