Functional Activity of Non-Proliferating Mesenchymal Stromal Cells Cultured at Different Densities
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-021-05102-w
Abstract: We analyzed the state of intracellular compartments and production of cytokines in MSC depending on the culture density. MSC were growth-arrested with mitomycin C and seeded at a density of 300-7000 cell/cm2. MSC in low-density… read more here.
Keywords: mesenchymal stromal; proliferating mesenchymal; non proliferating; density ... See more keywords
Antihistamines Modulate Functional Activity of Macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-021-05150-2
Abstract: We compared the effects of the first-, second- and third-generation antihistamines in different doses on enzyme activity and cytokine production by macrophages and their death using an in vitro model. It was found that decreasing… read more here.
Keywords: activity macrophages; generation; antihistamines modulate; functional activity ... See more keywords
Effect of hypothermia on the functional activity of liver mitochondria of grass snake (Natrix natrix): inhibition of succinate-fueled respiration and K+ transport, ROS-induced activation of mitochondrial permeability transition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-019-09796-6
Abstract: The article considers the comparative analysis of the functional activity of mitochondria isolated from the liver of grass snakes, Natrix natrix (Linnaeus, 1758) that were kept at different temperatures (23–26 °C and 4-5 °C). It was found… read more here.
Keywords: grass; liver mitochondria; inhibition; respiration ... See more keywords
Probing the Functional Activity Limits of Biomolecules Under Electron Irradiation
Sign Up to like & getrecommendations! Published in 2019 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927619008286
Abstract: Liquid cell transmission electron microscopy (LC-TEM) has the potential to allow for high resolution imaging of biological dynamics in a fully hydrated environment. While electrons can allow for subnanometer spatial resolution, one drawback of their… read more here.
Keywords: microscopy; activity limits; functional activity; probing functional ... See more keywords
Determination of the Relationship between Expression and Functional Activity of Multidrug Resistance-Associated Protein 1 using Scanning Electrochemical Microscopy.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b01601
Abstract: Cancer cells can develop multidrug resistance (MDR) after prolonged exposure to chemotherapeutic drugs, which is a severe impediment to successful treatment. MDR is typically associated with transmembrane proteins mediating efflux of administered drugs, thereby keeping… read more here.
Keywords: functional activity; multidrug resistance; cell; microscopy ... See more keywords
Functional Characterization of Human Peptide/Histidine Transporter 1 in Stably Transfected MDCK Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00728
Abstract: The proton-coupled oligopeptide transporter PHT1 (SLC15A4), which facilitates cross-membrane transport of histidine and small peptides from inside the endosomes or lysosomes to cytosol, plays an important role in intracellular peptides homeostasis and innate immune responses.… read more here.
Keywords: stably transfected; histidine; hpht1; mdck cells ... See more keywords
Mechanistic perspective and functional activity of insulin in amylin aggregation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00481a
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c8sc00481a
Abstract: This work provides the first-ever complete atomic model of insulin–amylin aggregates, identifying the specific interactions that stabilize the insulin–amylin complex. read more here.
Keywords: mechanistic perspective; perspective functional; functional activity; insulin amylin ... See more keywords
Functional brain activity is highly associated with cortical myelination in neonates.
Sign Up to like & getrecommendations! Published in 2022 at "Cerebral cortex"
DOI: 10.1093/cercor/bhac321
Abstract: Functional organization of the human cerebral cortex is highly constrained by underlying brain structures, but how functional activity is associated with different brain structures during development is not clear, especially at the neonatal stage. Since… read more here.
Keywords: cerebral cortex; brain; functional activity; activity ... See more keywords
HLA‐DR+ NK cells are mostly characterized by less mature phenotype and high functional activity
Sign Up to like & getrecommendations! Published in 2018 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.1032
Abstract: NK cells change their phenotype and functional characteristics during activation. In this work, we searched for a relationship of HLA‐DR expression with differentiation stages and functional activity of NK cells ex vivo and stimulated in… read more here.
Keywords: hla expression; cells mostly; hla; expression ... See more keywords
Intraintestinal Analysis of the Functional Activity of Microbiomes and Its Application to the Common Marmoset Intestine
Sign Up to like & getrecommendations! Published in 2022 at "mSystems"
DOI: 10.1128/msystems.00520-22
Abstract: We developed an analysis method that integrates metagenomes and metatranscriptomes from multiple intestinal sites to elucidate how microbial function varies along the intestinal tract. This method enables spatial covariation analysis of the functional activity of… read more here.
Keywords: intestinal sites; functional activity; analysis; activity microbiomes ... See more keywords
Regulation of the peritoneal macrophage functional activity by the MP-5 and MP-6 myelopeptides under stress
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biological Sciences"
DOI: 10.1134/s0012496617040123
Abstract: In mice, two-hour immobilization stress inhibited zymosan-induced production by macrophages of the oxygen radicals and cytokine IL-1β. After myelopeptides MP-5 and MP-6 were administered into mice, the stress-induced inhibition of the reactive oxygen species (ROS)… read more here.
Keywords: macrophage functional; peritoneal macrophage; stress; functional activity ... See more keywords