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   Articles with "functional activity" as a keyword



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Functional Activity of Non-Proliferating Mesenchymal Stromal Cells Cultured at Different Densities

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recommendations! Published in 2021 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-021-05102-w

Abstract: We analyzed the state of intracellular compartments and production of cytokines in MSC depending on the culture density. MSC were growth-arrested with mitomycin C and seeded at a density of 300-7000 cell/cm2. MSC in low-density… read more here.

Keywords: mesenchymal stromal; proliferating mesenchymal; non proliferating; density ... See more keywords
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Antihistamines Modulate Functional Activity of Macrophages.

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recommendations! Published in 2021 at "Bulletin of experimental biology and medicine"

DOI: 10.1007/s10517-021-05150-2

Abstract: We compared the effects of the first-, second- and third-generation antihistamines in different doses on enzyme activity and cytokine production by macrophages and their death using an in vitro model. It was found that decreasing… read more here.

Keywords: activity macrophages; generation; antihistamines modulate; functional activity ... See more keywords

Effect of hypothermia on the functional activity of liver mitochondria of grass snake (Natrix natrix): inhibition of succinate-fueled respiration and K+ transport, ROS-induced activation of mitochondrial permeability transition

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recommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"

DOI: 10.1007/s10863-019-09796-6

Abstract: The article considers the comparative analysis of the functional activity of mitochondria isolated from the liver of grass snakes, Natrix natrix (Linnaeus, 1758) that were kept at different temperatures (23–26 °C and 4-5 °C). It was found… read more here.

Keywords: grass; liver mitochondria; inhibition; respiration ... See more keywords

Probing the Functional Activity Limits of Biomolecules Under Electron Irradiation

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recommendations! Published in 2019 at "Microscopy and Microanalysis"

DOI: 10.1017/s1431927619008286

Abstract: Liquid cell transmission electron microscopy (LC-TEM) has the potential to allow for high resolution imaging of biological dynamics in a fully hydrated environment. While electrons can allow for subnanometer spatial resolution, one drawback of their… read more here.

Keywords: microscopy; activity limits; functional activity; probing functional ... See more keywords

Determination of the Relationship between Expression and Functional Activity of Multidrug Resistance-Associated Protein 1 using Scanning Electrochemical Microscopy.

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recommendations! Published in 2017 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.7b01601

Abstract: Cancer cells can develop multidrug resistance (MDR) after prolonged exposure to chemotherapeutic drugs, which is a severe impediment to successful treatment. MDR is typically associated with transmembrane proteins mediating efflux of administered drugs, thereby keeping… read more here.

Keywords: functional activity; multidrug resistance; cell; microscopy ... See more keywords

Functional Characterization of Human Peptide/Histidine Transporter 1 in Stably Transfected MDCK Cells.

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recommendations! Published in 2018 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.7b00728

Abstract: The proton-coupled oligopeptide transporter PHT1 (SLC15A4), which facilitates cross-membrane transport of histidine and small peptides from inside the endosomes or lysosomes to cytosol, plays an important role in intracellular peptides homeostasis and innate immune responses.… read more here.

Keywords: stably transfected; histidine; hpht1; mdck cells ... See more keywords

Mechanistic perspective and functional activity of insulin in amylin aggregation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00481a

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recommendations! Published in 2018 at "Chemical Science"

DOI: 10.1039/c8sc00481a

Abstract: This work provides the first-ever complete atomic model of insulin–amylin aggregates, identifying the specific interactions that stabilize the insulin–amylin complex. read more here.

Keywords: mechanistic perspective; perspective functional; functional activity; insulin amylin ... See more keywords

Chemical proteomics for a comprehensive understanding of functional activity and the interactome.

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recommendations! Published in 2025 at "Chemical Society reviews"

DOI: 10.1039/d5cs00381d

Abstract: Traditional mass spectrometry (MS)-based proteomics aims to detect and measure protein expression on a global scale and elucidate the link between protein function and phenotypic characteristics. Although advances in MS technology have significantly broadened the… read more here.

Keywords: functional activity; protein; proteomics comprehensive; chemical proteomics ... See more keywords

Functional brain activity is highly associated with cortical myelination in neonates.

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recommendations! Published in 2022 at "Cerebral cortex"

DOI: 10.1093/cercor/bhac321

Abstract: Functional organization of the human cerebral cortex is highly constrained by underlying brain structures, but how functional activity is associated with different brain structures during development is not clear, especially at the neonatal stage. Since… read more here.

Keywords: cerebral cortex; brain; functional activity; activity ... See more keywords

HLA‐DR+ NK cells are mostly characterized by less mature phenotype and high functional activity

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recommendations! Published in 2018 at "Immunology and Cell Biology"

DOI: 10.1111/imcb.1032

Abstract: NK cells change their phenotype and functional characteristics during activation. In this work, we searched for a relationship of HLA‐DR expression with differentiation stages and functional activity of NK cells ex vivo and stimulated in… read more here.

Keywords: hla expression; cells mostly; hla; expression ... See more keywords

Metabolomics Analysis of Functional Activity Changes in Residual Tumour Cells After IOCS Treatment

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recommendations! Published in 2025 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.70452

Abstract: Hepatocellular carcinoma (HCC) is a serious and often lethal cancer, particularly in patients with chronic liver disease. Currently, no specific treatment has been utilised to prevent HCC. The detailed mechanism of HCC is still elusive,… read more here.

Keywords: treatment; iocs treatment; functional activity; hcc ... See more keywords