Single‐Cell Sequencing Reveals Functional Alterations in Tuberculosis
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202305592
Abstract: Despite its importance, the functional heterogeneity surrounding the dynamics of interactions between mycobacterium tuberculosis and human immune cells in determining host immune strength and tuberculosis (TB) outcomes, remains far from understood. This work now describes… read more here.
Keywords: cell sequencing; single cell; sequencing reveals; functional alterations ... See more keywords
Ecotoxicoproteomic assessment of the functional alterations caused by chronic metallic exposures in gammarids.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental pollution"
DOI: 10.1016/j.envpol.2017.03.006
Abstract: Very few ecotoxicological studies have been performed on long-term exposure under controlled conditions, hence limiting the assessment of the impact of chronic and diffuse chemical pressures on the health of aquatic organisms. In this study,… read more here.
Keywords: functional alterations; assessment functional; proteins involved; long term ... See more keywords
Brain functional alterations observed 4-weekly in major depressive disorder following antidepressant treatment.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2019.04.001
Abstract: BACKGROUND Major depressive disorder (MDD) is a heterogeneous condition. Identifying the brain responses to antidepressant treatment is of particular interest as these may represent potential neural networks related to treatment response, forming one aspect of… read more here.
Keywords: functional alterations; depressive disorder; treatment; major depressive ... See more keywords
Architectural and functional alterations of the small intestinal mucosa in classical Whipple’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Mucosal Immunology"
DOI: 10.1038/mi.2017.6
Abstract: Classical Whipple’s disease (CWD) affects the gastrointestinal tract and rather elicits regulatory than inflammatory immune reactions. Mechanisms of malabsorption, diarrhea, and systemic immune activation are unknown. We here analyzed mucosal architecture, barrier function, and immune… read more here.
Keywords: whipple disease; architectural functional; classical whipple; functional alterations ... See more keywords
Personalized biomarkers of multiscale functional alterations in temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-65042-1
Abstract: Temporal lobe epilepsy (TLE) presents with substantial inter-patient variability in clinical and neuroimaging manifestations. This multicenter study examined inter-individual differences in spatial patterns of intrinsic brain function in TLE using normative modeling at multiple spatial… read more here.
Keywords: lobe epilepsy; temporal lobe; functional alterations; personalized biomarkers ... See more keywords
Neurologic impairment and brain microstructural-functional alterations in infantile spasms: A multimodal magnetic resonance imaging study.
Sign Up to like & getrecommendations! Published in 2025 at "Epilepsia"
DOI: 10.1111/epi.18620
Abstract: Infantile spasms (IS) are associated with significant neurodevelopmental impairments, yet the underlying brain microstructural and functional alterations remain poorly understood. This study aimed to investigate gray and white matter abnormalities in IS patients and their… read more here.
Keywords: infantile spasms; functional alterations; brain microstructural; microstructural functional ... See more keywords
Functional Alterations in Gray Matter Networks Mediated by White Matter During the Aging Process
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Neuroimaging"
DOI: 10.1111/jon.70036
Abstract: Extensive research has been carried out to investigate changes in various gray matter (GM) regions during the aging process using resting‐state functional MRI. However, the impact of aging on the functional connectivity (FC) between white… read more here.
Keywords: aging process; white matter; gray matter; alterations gray ... See more keywords
Quantitative analysis of morphological and functional alterations of the meibomian glands in eyes with marginal entropion
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0267118
Abstract: Purpose To quantitatively analyze morphological and functional alterations of the meibomian glands in eyes with marginal entropion and their changes after surgery. Methods Sixty eyes of 52 patients with marginal entropion and underwent meibography and… read more here.
Keywords: marginal entropion; morphological functional; alterations meibomian; entropion ... See more keywords
Screening of structural and functional alterations in duckweed (Lemna minor) induced by per- and polyfluoroalkyl substances (PFASs) with FTIR spectroscopy.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.2139/ssrn.4221609
Abstract: As a class of common emerging pollutants, per- and polyfluoroalkyl substances (PFASs) and their alternatives have been widely detected in various environmental matrices, exhibiting a great threat to the ecological environment and human health. Nevertheless,… read more here.
Keywords: per polyfluoroalkyl; spectroscopy; polyfluoroalkyl substances; functional alterations ... See more keywords
Uncovering the significance of expanded CD8+ large granular lymphocytes in inclusion body myositis: Insights into T cell phenotype and functional alterations, and disease severity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1153789
Abstract: Introduction Inclusion body myositis (IBM) is a progressive inflammatory myopathy characterised by skeletal muscle infiltration and myofibre invasion by CD8+ T lymphocytes. In some cases, IBM has been reported to be associated with a systemic… read more here.
Keywords: ibm patients; functional alterations; large granular; inclusion body ... See more keywords
Morphological and Functional Alterations Induced by Two Ecologically Relevant Concentrations of Lead on Danio rerio Gills
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169165
Abstract: Lead (Pb), due to its high toxicity and bioaccumulation tendency, is one of the top three pollutants of concern for both humans and wildlife and occupies second place in the Priority List of Hazardous Substances.… read more here.
Keywords: induced two; functional alterations; morphological functional; relevant concentrations ... See more keywords