Identification of differentially expressed genes and functional annotations associated with metastases of the uveal melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29250
Abstract: Uveal melanoma (UVM) is an adult intraocular malignancy which is the most frequent and has a high tendency for metastasis. This study aims to develop significant differential gene subnetwork between primary and metastatic UVM to… read more here.
Keywords: functional annotations; metastatic uvm; uveal melanoma; primary metastatic ... See more keywords
KampoDB, database of predicted targets and functional annotations of natural medicines
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29516-1
Abstract: Natural medicines (i.e., herbal medicines, traditional formulas) are useful for treatment of multifactorial and chronic diseases. Here, we present KampoDB (http://wakanmoview.inm.u-toyama.ac.jp/kampo/), a novel platform for the analysis of natural medicines, which provides various useful scientific… read more here.
Keywords: constituent compounds; functional annotations; target proteins; natural medicines ... See more keywords
PALM: a powerful and adaptive latent model for prioritizing risk variants with functional annotations
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad068
Abstract: Abstract Motivation The findings from genome-wide association studies (GWASs) have greatly helped us to understand the genetic basis of human complex traits and diseases. Despite the tremendous progress, much effects are still needed to address… read more here.
Keywords: powerful adaptive; adaptive latent; functional annotations; model ... See more keywords
PDBe-KB: a community-driven resource for structural and functional annotations
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz853
Abstract: Abstract The Protein Data Bank in Europe-Knowledge Base (PDBe-KB, https://pdbe-kb.org) is a community-driven, collaborative resource for literature-derived, manually curated and computationally predicted structural and functional annotations of macromolecular structure data, contained in the Protein Data… read more here.
Keywords: community; pdbe; community driven; functional annotations ... See more keywords
A novel assembly pipeline and functional annotations for targeted sequencing: A case study on the globally threatened Margaritiferidae (Bivalvia: Unionida).
Sign Up to like & getrecommendations! Published in 2023 at "Molecular ecology resources"
DOI: 10.1111/1755-0998.13802
Abstract: The proliferation of genomic sequencing approaches has significantly impacted the field of phylogenetics. Target capture approaches provide a cost-effective, fast and easily applied strategy for phylogenetic inference of non-model organisms. However, several existing target capture… read more here.
Keywords: new pipeline; target capture; functional annotations; novel assembly ... See more keywords
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Sign Up to like & getrecommendations! Published in 2019 at "Genome Biology"
DOI: 10.1186/s13059-019-1835-8
Abstract: BackgroundThe Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function.ResultsHere, we report on the results of the third CAFA challenge, CAFA3, that… read more here.
Keywords: functional annotations; protein function; new functional; cafa challenge ... See more keywords
Leveraging functional annotations in genetic risk prediction for human complex diseases
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005589
Abstract: Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite the identification of thousands of… read more here.
Keywords: annotations genetic; functional annotations; risk prediction; prediction ... See more keywords
Community Structure and Functional Annotations of the Skin Microbiome in Healthy and Diseased Catfish, Heteropneustes fossilis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.856014
Abstract: The skin mucosa of fish serves as a primary barrier against pathogens. In lesion sites in diseased fish, the mucosal barrier is expected to be compromised, with a substantial presence of potential pathogens. An understanding… read more here.
Keywords: skin microbiome; diseased fish; heteropneustes fossilis; catfish heteropneustes ... See more keywords