3D bioprinting of functional cell-laden bioinks and its application for cell-alignment and maturation
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100588
Abstract: Abstract Biomedical scaffolds should provide physical, biological, and topographical cues to seeded or laden cells to successfully mimic the physiochemical properties of native tissues. Cell-laden scaffolds, in particular, can efficiently deliver various cells safely to… read more here.
Keywords: bioink; cell laden; alignment maturation; cell ... See more keywords
Synaptotagmins Tweak Functional β Cell Maturation.
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DOI: 10.1016/j.devcel.2018.04.018
Abstract: Immature β cells secrete insulin at a lower glucose threshold compared to mature β cells. In this issue of Developmental Cell, Huang et al. (2018) show that the increase in glucose threshold during β cell maturation… read more here.
Keywords: synaptotagmins tweak; cell maturation; tweak functional; cell ... See more keywords
Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function
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DOI: 10.2337/db17-1352
Abstract: Loss of functional β-cell mass is an early feature of type 1 diabetes. To release insulin, β-cells require soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes, as well as SNARE complex regulatory proteins like double… read more here.
Keywords: cell mass; doc2b; cell; functional cell ... See more keywords
Time Course of Normalization of Functional β-Cell Capacity in the Diabetes Remission Clinical Trial After Weight Loss in Type 2 Diabetes
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DOI: 10.2337/dc19-0371
Abstract: OBJECTIVE To assess functional β-cell capacity in type 2 diabetes during 2 years of remission induced by dietary weight loss. RESEARCH DESIGN AND METHODS A Stepped Insulin Secretion Test with Arginine was used to quantify… read more here.
Keywords: remission; weight loss; cell capacity; pmol min ... See more keywords
Good Cop, Bad Cop: The Opposing Effects of Macrophage Activation State on Maintaining or Damaging Functional β-Cell Mass
Sign Up to like & getrecommendations! Published in 2020 at "Metabolites"
DOI: 10.3390/metabo10120485
Abstract: Loss of functional β-cell mass is a hallmark of Type 1 and Type 2 Diabetes. Macrophages play an integral role in the maintenance or destruction of pancreatic β-cells. The effect of the macrophage β-cell interaction… read more here.
Keywords: cop; cell mass; macrophage; cell ... See more keywords