Identification and functional comparison of novel alternatively spliced isoforms of human YAP.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13618
Abstract: As a key effector of the Hippo pathway, yes‐associated protein (YAP) is a major regulator of cell proliferation and apoptosis. In this study, 23 hYAP isoforms were identified in HEK293 cells, with 14 isoforms being… read more here.
Keywords: identification functional; alternatively spliced; novel alternatively; hyap isoforms ... See more keywords
Functional comparison of human ACVR1 and zebrafish Acvr1l FOP‐associated variants in embryonic zebrafish
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DOI: 10.1002/dvdy.566
Abstract: Fibrodysplasia ossificans progressiva (FOP), a rare disease characterized by progressive heterotopic ossification of muscle and connective tissues, is caused by autosomal dominant activating mutations in the type I receptor, ACVR1/ALK2. The classic human FOP variant,… read more here.
Keywords: comparison human; zebrafish; fop; human acvr1 ... See more keywords
Functional Comparison of Short and Long Isoforms of the TRF2 Protein in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2019 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672919030165
Abstract: TRF2 protein (TBP-related factor 2) can substitute for TBP forming alternative transcription initiation complexes on TATA-less promoters, including the promoters of histone H1 and piRNA clusters required for transposon repression. The Drosophilatrf2 gene codes for… read more here.
Keywords: short long; trf2; comparison short; trf2 protein ... See more keywords
Functional Comparison between Healthy and Multiple Myeloma Adipose Stromal Cells
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DOI: 10.1155/2020/4173578
Abstract: Multiple myeloma (MM) is an incurable B cell neoplasia characterized by the accumulation of tumor plasma cells within the bone marrow (BM). As a consequence, bone osteolytic lesions develop in 80% of patients and remain… read more here.
Keywords: stromal cells; functional comparison; multiple myeloma; bone ... See more keywords
Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes
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DOI: 10.1242/bio.059016
Abstract: ABSTRACT Cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) offer an attractive platform for cardiovascular research. Patient-specific iPSC-CMs are very useful for studying disease development, and bear potential for disease diagnostics, prognosis evaluation and development… read more here.
Keywords: morpho functional; ipsc cms; cms; differentiation ... See more keywords