Identification of Disease-Causing Mutations by Functional Complementation of Patient-Derived Fibroblast Cell Lines.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6824-4_24
Abstract: Diagnosis of mitochondrial disorders is still hampered by their phenotypic and genotypic heterogeneity. In many cases, exome sequencing, the state-of-the-art method for genetically diagnosing mitochondrial disease patients, does not allow direct identification of the disease-associated… read more here.
Keywords: disease causing; cell lines; disease; functional complementation ... See more keywords
Coinfection in the host can result in functional complementation between live vaccines and virulent virus
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2082645
Abstract: ABSTRACT One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines.… read more here.
Keywords: vaccines virulent; virulent virus; complementation; functional complementation ... See more keywords
Functional Complementation of Anti-Adipogenic Phytonutrients for Obesity Prevention and Management
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DOI: 10.3390/nu14204325
Abstract: Obesity is an established risk factor for metabolic disease. This study explores the functional complementation of anti-adipogenic phytonutrients for obesity prevention and management. Nine phytonutrients were selected based on their ability to affect the expression… read more here.
Keywords: adipogenic phytonutrients; anti adipogenic; functional complementation; obesity ... See more keywords