Plasma phosphorylated tau181 predicts cognitive and functional decline
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51695
Abstract: To determine if plasma tau phosphorylated at threonine 181 (p‐tau181) distinguishes pathology‐confirmed Alzheimer's disease (AD) from normal cognition (NC) adults, to test if p‐tau181 predicts cognitive and functional decline, and to validate findings in an… read more here.
Keywords: cognitive functional; predicts cognitive; tau181 predicts; plasma ... See more keywords
Water T2 could predict functional decline in patients with dysferlinopathy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13063
Abstract: Water T2 (T2H2O) mapping is increasingly being used in muscular dystrophies to assess active muscle damage. It has been suggested as a surrogate outcome measure for clinical trials. Here, we investigated the prognostic utility of… read more here.
Keywords: water; predict functional; decline patients; water could ... See more keywords
Value of FDG-PET scans of non-demented patients in predicting rates of future cognitive and functional decline
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3634-3
Abstract: PurposeThe aim of this study was to examine the value of fluorodeoxyglucose (FDG) positron emission tomography (PET) in predicting subsequent rates of functional and cognitive decline among subjects considered cognitively normal (CN) or clinically diagnosed… read more here.
Keywords: pet; value; fdg pet; decline ... See more keywords
Geriatric Assessment and Functional Decline in Older Patients with Lung Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Lung"
DOI: 10.1007/s00408-017-0025-2
Abstract: PurposeOlder patients with lung cancer are a heterogeneous population making treatment decisions complex. This study aims to evaluate the value of geriatric assessment (GA) as well as the evolution of functional status (FS) in older… read more here.
Keywords: patients lung; decline; geriatric assessment; lung cancer ... See more keywords
Gender Differences in Trajectories of Lower Extremity Function in Older Adults: Findings From the International Mobility in Aging Study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Medical Directors Association"
DOI: 10.1016/j.jamda.2019.04.014
Abstract: OBJECTIVES We examined the lower extremity function trajectories of older men and women over 4 years and baseline predictors of these trajectories. DESIGN Longitudinal analysis of an international cohort study. SETTINGS AND PARTICIPANTS Older adults from… read more here.
Keywords: physical performance; gender; decline; functional decline ... See more keywords
Functional decline in older patients with cancer receiving chemotherapy: A multicenter prospective study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2017.02.010
Abstract: OBJECTIVES This study aims to evaluate the evolution of functional status (FS) 2 to 3months after initiation of chemotherapy, to identify factors associated with functional decline during chemotherapy treatment and to investigate the prognostic value… read more here.
Keywords: chemotherapy; adl; cancer receiving; iadl ... See more keywords
Social relationships and functional status among Japanese elderly adults living in a suburban area.
Sign Up to like & getrecommendations! Published in 2019 at "Public health"
DOI: 10.1016/j.puhe.2019.09.016
Abstract: OBJECTIVES Social relationships may help in maintaining functional status among older adults. This study examined the types of social relationships that were related to functional status among Japanese community-dwelling older adults. STUDY DESIGN This is… read more here.
Keywords: status; social relationships; functional status; among japanese ... See more keywords
P115: Limiting functional decline in seniors evaluated for minor injuries in the ED
Sign Up to like & getrecommendations! Published in 2017 at "Canadian Journal of Emergency Medicine"
DOI: 10.1017/cem.2017.317
Abstract: Introduction: In its prospective cohorts of independent seniors with minor injuries, the CETIe (Canadian Emergency Team Initiative) has shown that minor injuries trigger a spiral of mobility and functional decline in 18% of those seniors… read more here.
Keywords: mobility; decline seniors; minor injuries; functional decline ... See more keywords
Growth-associated protein 43 is associated with faster functional decline among amyloid-positive individuals with objectively defined subtle cognitive decline and mild cognitive impairment.
Sign Up to like & getrecommendations! Published in 2025 at "Neuropsychology"
DOI: 10.1037/neu0000981
Abstract: OBJECTIVE Objectively defined subtle cognitive decline (Obj-SCD) is an emerging classification that may identify individuals at risk for future decline and progression to Alzheimer's disease prior to a diagnosis of mild cognitive impairment (MCI). Growth-associated… read more here.
Keywords: obj scd; mci; functional decline; subtle cognitive ... See more keywords
Protein aggregation contributes to aging in C. elegans
Sign Up to like & getrecommendations! Published in 2019 at "Lab Animal"
DOI: 10.1038/s41684-019-0335-5
Abstract: Aging is associated with a progressive decline in many physiological functions, which decreases the quality of life of elderly individuals. The mechanisms underlying aging are still unclear, hampering the development of strategies to delay functional… read more here.
Keywords: protein; aggregation; age; protein aggregation ... See more keywords
U-shaped relationship between body mass index and intracerebral hemorrhage-related functional decline
Sign Up to like & getrecommendations! Published in 2024 at "Neurological Research"
DOI: 10.1080/01616412.2025.2472843
Abstract: ABSTRACT Background Body mass index (BMI) is associated with the sites of intracerebral hemorrhage (ICH), which affect functional decline. However, the optimal BMI range for minimizing functional decline remains unclear. This study aimed to clarify… read more here.
Keywords: body mass; relationship; functional decline; bmi ... See more keywords