Using Functional Genetics in Haploid Cells for Drug Target Identification.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9145-7_1
Abstract: Pooled genetic screens are a powerful tool to identify targets for drug development as well as chemogenetic interactions. Various complementary methods for mutagenesis are available to generate highly complex cell populations, including mRNA knockdown, directed… read more here.
Keywords: genetics; using functional; drug; haploid cells ... See more keywords
CRISPR/Cas9 Targeted Mutagenesis for Functional Genetics in Maize
Sign Up to like & getrecommendations! Published in 2021 at "Plants"
DOI: 10.3390/plants10040723
Abstract: The CRISPR/Cas9-based system for targeted mutagenesis has become an indispensable tool for functional genetics in plants. CRISPR/Cas9 allows users to generate loss-of-function alleles in genes of interest with precision and in a simple-to-use system. This… read more here.
Keywords: crispr cas9; genetics; functional genetics; targeted mutagenesis ... See more keywords