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Published in 2022 at "Molecular reproduction and development"
DOI: 10.1002/mrd.23625
Abstract: Reproductive failure is the main reason for culling females in swine herds and is both a financial and sustainability issue. Because reproductive traits are complex and lowly to moderately heritable, genomic selection within populations can…
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Keywords:
reproduction pigs;
candidate genes;
genomics reproduction;
pigs yet ... See more keywords
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Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6427-7_6
Abstract: The abundance of existing functional genomics studies permits an integrative approach to interpreting and resolving the results of diverse systems genetics studies. However, a major challenge lies in assembling and harmonizing heterogeneous data sets across…
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Keywords:
geneweaver org;
integrative functional;
genetics;
functional genomics ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7278-4_8
Abstract: Online tools and databases play an essential role in the promotion of functional genomics studies. Several resources for information regarding Brachypodium distachyon (Brachypodium) are available on the Web. In this chapter, we focus on recently…
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Keywords:
information;
information resources;
functional genomics;
brachypodium ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7724-6_7
Abstract: Functional genomics is the study of the function of genes on a genome-wide level. Reporter gene assays can be utilized in this context to dissect signaling cascades, find new drug targets, or decipher the function…
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Keywords:
genome wide;
reporter gene;
functional genomics;
biology ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7724-6_8
Abstract: Transfectable functional genomics libraries are traditionally the workhorses of functional genomics screening using reporter gene assays. These libraries offer insight into fundamental cellular processes governing health and disease and can be utilized in an arrayed…
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Keywords:
reporter gene;
genomics libraries;
functional genomics;
transfectable functional ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8633-0_17
Abstract: Flowering time is an important trait that influences adaptation and yield in many crop legumes. Both the inherent earliness of flowering and the degree to which it is responsive to environmental factors determine both the…
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Keywords:
functional genomics;
time;
flowering time;
medicago truncatula ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8633-0_2
Abstract: Many researchers have sought along the last two decades a legume species that could serve as a model system for genetic studies to resolve specific developmental or metabolic processes that cannot be studied in other…
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Keywords:
genomics tools;
functional genomics;
model;
medicago truncatula ... See more keywords
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Published in 2019 at "Molecular Breeding"
DOI: 10.1007/s11032-019-1045-9
Abstract: Protein kinases (PKs) belonging to a large superfamily play vital roles in plant development and stress tolerance, whereas only a small number of PKs have been functionally studied in wheat. Genome-wide survey and characterization of…
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Keywords:
wheat;
analysis;
functional genomics;
expression ... See more keywords
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Published in 2022 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2021.101535
Abstract: Women live longer than men but experience greater disability and a longer period of illness as they age. Despite clear sex differences in aging, the impact of pregnancy and its complications, such as preeclampsia, on…
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Keywords:
epidemiology;
maternal aging;
functional genomics;
pregnancy ... See more keywords
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Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.06.269
Abstract: With thanks to the EAS for support in the form of a Young Investigator Fellowship. Rafael Graca acknowledges financial support from FCT (PD/BD/131427/2017).
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Keywords:
cohort mutation;
mutation negative;
negative patients;
genomics cohort ... See more keywords
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Published in 2022 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2021.103705
Abstract: Functional genomics is an essential tool for elucidating the structure and function of genes in any living organism. Here, we review the use of different gene manipulation techniques in functional genomics of Acari (mites and…
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Keywords:
manipulation techniques;
crispr cas9;
functional genomics;
gene manipulation ... See more keywords