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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209608119
Abstract: Significance Helicases are ubiquitous NTP-dependent enzymes that disrupt nucleic acid (NA) helices and NA–protein interactions. Despite the implication of helicases in many cellular processes and diseases, their target repertoires and determinants of functional specialization often…
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Keywords:
framework discovery;
helicase substrates;
scalable framework;
functional helicase ... See more keywords