Functional Human Oocytes Generated by Transfer of Polar Body Genomes.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2016.10.001
Abstract: Oocyte defects lie at the heart of some forms of infertility and could potentially be addressed therapeutically by alternative routes for oocyte formation. Here, we describe the generation of functional human oocytes following nuclear transfer… read more here.
Keywords: oocytes generated; functional human; human oocytes; polar body ... See more keywords
Visualizing molecules of functional human profilin
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DOI: 10.1101/2021.09.01.458557
Abstract: Profilin-1 (PFN1) is a cytoskeletal protein that regulates the dynamics of actin and microtubule assembly. Thus, PFN1 is essential for the normal division, motility, and morphology of cells. Unfortunately, conventional fusion and direct labeling strategies… read more here.
Keywords: molecules functional; biochemical assays; pfn1; visualizing molecules ... See more keywords
Adapting Physiology in Functional Human Islet Organogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.854604
Abstract: Generation of three-dimensional (3D)-structured functional human islets is expected to be an alternative cell source for cadaveric human islet transplantation for the treatment of insulin-dependent diabetes. Human pluripotent stem cells (hPSCs), such as human embryonic… read more here.
Keywords: human islets; physiology; human islet; functional human ... See more keywords