Functional Interaction Network Construction and Analysis for Disease Discovery.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6783-4_11
Abstract: Network-based approaches project seemingly unrelated genes or proteins onto a large-scale network context, therefore providing a holistic visualization and analysis platform for genomic data generated from high-throughput experiments, reducing the dimensionality of data via using… read more here.
Keywords: interaction network; network; analysis; network construction ... See more keywords
The functional interaction of the brain default network with motor networks is modified by aging
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2019.112048
Abstract: Motor disturbance is a major source of injury in older adults, a fact facilitated by the interfering action of cognitive activities on ongoing motor tasks. The present work studies the influence of aging on the… read more here.
Keywords: network; dmn; motor networks; inactivation ... See more keywords
Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007029
Abstract: Key Points A patient with a severe form of telomere biology disorder has compound heterozygous variants in TERT that interact functionally. The functional interaction between alleles explains the much more extreme phenotype in the proband… read more here.
Keywords: biology disorder; compound heterozygous; telomere biology; functional interaction ... See more keywords
Functional interaction between macrophages and hepatocytes dictate the outcome of liver fibrosis
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DOI: 10.26508/lsa.202000803
Abstract: Xie et al demonstrate opposite outcomes on liver fibrosis due to deletion of c-Jun in hepatocytes alone or along with Kupffer cells, highlighting the functional interaction between these cell types in regulating the fibrotic process,… read more here.
Keywords: jun hepatocytes; jun; functional interaction; liver fibrosis ... See more keywords
Functional Interaction Between Drosophila Olfactory Sensory Neurons and Their Support Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.789086
Abstract: Insects detect volatile chemicals using antennae, which house a vast variety of olfactory sensory neurons (OSNs) that innervate hair-like structures called sensilla where odor detection takes place. In addition to OSNs, the antenna also hosts… read more here.
Keywords: support; sensory neurons; olfactory sensory; support cells ... See more keywords
Microfluidic Bi-Layer Platform to Study Functional Interaction between Co-Cultured Neural Networks with Unidirectional Synaptic Connectivity
Sign Up to like & getrecommendations! Published in 2023 at "Micromachines"
DOI: 10.3390/mi14040835
Abstract: The complex synaptic connectivity architecture of neuronal networks underlies cognition and brain function. However, studying the spiking activity propagation and processing in heterogeneous networks in vivo poses significant challenges. In this study, we present a… read more here.
Keywords: functional interaction; synaptic connectivity; network; activity ... See more keywords